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Biomedical Reviews

Nanoparticles reshape the biomedical industry

Parichehr Hassanzadeh, Fatemeh Atyabi, Rassoul Dinarvand

Abstract

Over the last decades, increasing interest has been attracted towards the nanotechnology which provide a set of promising research tools and theranostic approaches. Tremendous research efforts in nanofabrication technology have led to the production of biocompatible nanostructures and advanced carriers with various configurations for protection of the loaded biomolecules or drugs against the metabolism or excretion. Furthermore, controlled delivery and targeted therapy may result in the improved therapeutic effects against a variety of diseases and reduced adverse effects of drugs. The efficiency of protein drugs may be negatively affected by their limited transportation within the body and short half-lives. Application of nanoparticles may significantly improve the pharmacological profiles of protein drugs. In neurology, high-resolution imaging techniques, nanoengineered materials capable of interaction with the nervous systems, and nanopharmaceuticals with minimal toxicity and improved bioavailability may be of great theranostic significance. This may provide remarkable breakthroughs in the pharmaceutical industry and health-care system. In the present review, the significance of nanotechnology and modeling approaches in health-care system has been highlighted.

Keywords

nanomedicine, drug delivery, nanopharmaceuticals

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DOI: http://dx.doi.org/10.14748/bmr.v29.5846

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About The Authors

Parichehr Hassanzadeh
Tehran University of Medical Sciences, Tehran, Iran
Iran, Islamic Republic of

Nanotechnology Research Center, Faculty of Pharmacy

Fatemeh Atyabi
Tehran University of Medical Sciences, Tehran, Iran
Iran, Islamic Republic of

Nanotechnology Research Center, Faculty of Pharmacy

Department of Pharmaceutics, Faculty of Pharmacy

Rassoul Dinarvand
Tehran University of Medical Sciences, Tehran, Iran
Iran, Islamic Republic of

Nanotechnology Research Center, Faculty of Pharmacy

Department of Pharmaceutics, Faculty of Pharmacy

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