Scientific Online Resource System

Heart - Lung (Varna)

Alcohol septal ablation for hypertrophic obstructive cardiomyopathy

J. Sitar, L. Groch, N. Penkov, L. Dimitrova, R. Radoslavova


Hypertrophic obstructive cardiomyopathy (HOCM) is characterized by asymetric septal hypertrophy, systolic anterior motion (SAM) in echocardiography and gradient in the left ventricle output tract (LVOT).

Full Text


Sorajja P, Ommen SR, Holmes DR Jr et al. Survival after alcohol septal ablation for obstructive hypertrophic cardiomyopathy. Circulation. 2012;126(20):2374-80.

Fifer MA, Sigwart U. Controversies in cardiovascular medicine. Hypertrophic obstructive cardiomyopathy: alcohol septal ablation. Eur Heart J. 2011 May;32(9):1059-64.

Hess OM, Sigwart U. New treatment strategies for hypertrophic obstructive cardiomyopathy: alcohol ablation of the septum: the new gold standard? J Am Coll Cardiol. 2004 Nov 16;44(10):2054-5. Review.

Orme NM, Sorajja P, Dearani JA et al. Comparison of surgical septal myectomy to medical therapy alone in patients with hypertrophic cardiomyopathy and syncope.

Krejcí J, Groch L, Meluzín J et al. Non-pharmacologic therapy of hypertrophic obstructive cardiomyopathy--results of therapy based on percutaneous transluminal septal myocardial ablation compared with results of dual-chamber cardiac pacing. Vnitr Lek. 2006 Apr;52(4):313-20. Czech.

Alam M, Dokainish H, Lakkis N. Alcohol septal ablation for hypertrophic obstructive cardiomyopathy: a systematic review of published studies. J Interv Cardiol. 2006 Aug;19(4):319-27.

Veselka J, TomaÅ¡ov P, Zemánek D. Long-term effects of varying alcohol dosing in percutaneous septal ablation for obstructive hypertrophic cardiomyopathy: a randomized study with a follow-up up to 11 years. Can J Cardiol. 2011;27(6):763-7.

Veselka J, Tesar D, Urbanová T et al. Percutaneous transluminal septal myocardial ablation in the treatment of hypertrophic obstructive cardiomyopathy: short-term study. Vnitr Lek. 2001;47(7):437-43.



Font Size