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Heart - Lung (Varna)

Ischemic mitral regurgitation

N. Penkov, G. Kirilova


Ischemic mitral regurgitation (IMR) is a disease of the left ventricle. It could be a result of transient myocardial ischemia or acute myocardial infarction (AMI) with mechanical changes in one of the papillary muscles or subsequent myocardial remodeling. Regurgitation due to transient myocardial ischemia is reversible. Acute myocardial infarction, complicated by mechanical papillary muscle changes takes a dramatic and often fatal course. Left ventricle (LV) remodeling after acute myocardial infarction leads to chronic mitral regurgitation with dynamic behaviour - it could be influenced by medication and exercise. The incidence of IMR is unknown . The prognosis is poor especially in cases of moderate or severe regurgitation. Treatment includes optimal anti-ischemic medications or surgery - bypass plus valve reconstruction.


myocardial infarction, papillary muscle rupture, ventricular remodeling , mitral regurgitation

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