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Heart failure treatment in patients with thalassemia major

Mariya Stoyanova Dimova, Valeria Kaleva, Yavor Kashlov


The modern treatment of heart failure (HF) in patients with thalassemia is based on the prevention of cardiac impair- ment. Iron overload cardiomyopathy is the most serious and life-threatening complication of transfusion-dependent thalassemia, but due to its association with iron deposition it is reversible. Treatment includes chelation therapy and conventional medication for HF. Severely decompensated cases are treated in specialized centers.


thalassemia major, heart failure

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