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Cortical regions connected with autonomic cardiovascular regulation

Darina Georgieva-Hristova, Silva Andonova, Evgeniya Kalevska, Veselinka Nestorova, Ivan Dzedzev, Diana Radkova

Abstract

Violations of the autonomic nervous system are common in patients with cerebrovascular diseases and adversely affect the quality of life. The central autonomic network combines multiple reciprocally connected cortical, subcortical and stem structures. The insular cortex is involved in visceral motor and sensory regulation, including that of the cardiovascular system. Brain lesions including insula and other prefrontal cortical areas are particularly important in provoking arrhythmia. Stroke involving insular cortex is associated with poor prognosis. The right insular cortex plays a dominant role in modulating sympathetic tone and the left insular cortex in parasympathetic tone, which clinically correlates with more frequent arrhythmias and arrhythmic death after a stroke affecting the insula in the right hemisphere. The insular cortex is located in the middle cerebral artery and its structure is exposed to a high risk of injury.

Keywords

cortex insularis; cerebrovascular disease; arrhythmia; arterial hypertension; cardiac dysfunction

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DOI: http://dx.doi.org/10.14748/ssm.v47i1.1070

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About The Authors

Darina Georgieva-Hristova
Medical university of Varna
Bulgaria

Department of neurology and neuroscience

Silva Andonova
Medical university of Varna
Bulgaria

Department of neurology and neuroscience

Evgeniya Kalevska
Medical university of Varna
Bulgaria

Department of neurology and neuroscience

Veselinka Nestorova
Medical university of Varna
Bulgaria

Department of professional disease

Ivan Dzedzev
Medical university of Varna
Bulgaria

Department of professional disease

Diana Radkova
Medical university of Varna
Bulgaria

Department of infectious, epidemiology and tropical medicine

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