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Scripta Scientifica Medica

ПРОУЧВАНЕ ЕФЕКТИВНОСТТА НА ГАМА-ГЛОБУЛИНОВАТА ПРОФИЛАКТИКА НА ЕПИДЕМИЧНИЯ ХЕПАТИТ В ПРЕДЕПИДЕМИЧЕН ПЕРИОД

K. Kузмов, В. Христов, П. Kокошаров, Б. Дъков, С. Гълъбова, С. Kривцова

Abstract

Over the period 6-12 October, 1965 a series comprising 4638 school-children, from I to VI class inch, underwent one cubic centimeter 10% gammaglobulin injections each, with individual syringes, provided by the Research Institute of Epidemiology and Microbiology. A group of 4693 children were left for control purposes. The observation period for both groups lasted till September, 1966. During the first quarter, the epidemic hepatitis morbidity rate in the group with immunization was nil, whilst in the control group (without immunization) it reached the high figure 21.1 %00. During the second, third and fourth quarters, the morbidity among immunized was comparatively lower. The data recovered show that the effectiveness of the gamma-globulin prophylaxis during the pre-epidemic period is dependent on the epidemic hepatitis morbidity rate for the entire community. The sex morbidity among immunized subjects is equal, but shows a tendency for increase among school children which are not immunized.


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DOI: http://dx.doi.org/10.14748/ssm.v7i0.4986

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About The Authors

K. Kузмов

В. Христов

П. Kокошаров

Б. Дъков

С. Гълъбова

С. Kривцова

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