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Acute poisonings with neuroleptics in clinic of toxicology of military Medical academy Varna/Bulgaria registered for 20 year period

Kaloyan Georgiev, Marieta Georgieva, Petko Marinov, Diana Radkova

Abstract

Objective: This retrospective study was conducted to follow out acute intoxications with neuroleptics in Varna region, to assess the frequency and proportion depending on other drug and non-pharmacological poisoning.

Methods: The objects of the study are 193 patients with acute neuroleptic intoxication treated in the Clinic of toxicology - VMA-MBAL-Varna. The study is retrospective and covers a period of 20 years (1991-2010).

Results: Incidence of acute poisoning with neuroleptics is 7.5% of all drug poisoning and 2.5% of general poisoning. Poisoning occurs commonly in women and the majority of poisonings are in people of working age.

Conclusion: In recent years, there is a trend for an increase in the absolute number and the proportion of poisonings with neuroleptics. Lethality in these poisonings is not high and is 0.4 percent.


Keywords

acute poisoning; intoxication; medicines; neuroleptics; antipsychotics

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References

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DOI: http://dx.doi.org/10.14748/ssm.v47i1.751

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About The Authors

Kaloyan Georgiev
Medical university of Varna
Bulgaria

Department of Preclinical and clinical sciences, Sector Pharmacology and Toxicology, Faculty of Pharmacy, Medical University `Prof. Paraskev Stoianov`- Varna

Marieta Georgieva
Medical university of Varna
Bulgaria

Department of Preclinical and clinical sciences, Sector Pharmacology and Toxicology, Faculty of Pharmacy, Medical University `Prof. Paraskev Stoianov`- Varna

Petko Marinov
Medical university of Varna
Bulgaria

Department of Preclinical and clinical sciences, Sector Pharmacology and Toxicology, Faculty of Pharmacy, Medical University `Prof. Paraskev Stoianov`- Varna

Diana Radkova
Medical university of Varna
Bulgaria

Department of infectious diseases

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