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Early perioperative res ults in 53 cases of locally rec urrent colorectal cancer

V. Marinov, R. Gaydarski, K. Draganov, N. Katev, D. Rusenov, Y. Kolev, A. Petreska, B. Borisov, G. Chengalova, S. Lavchev, D. Penchev, D. Stoyanova, S. Tonev

Abstract

Purpose: The objective of this study was to analyze retrospectively the early perioperative results in a cohort of 53 patients with localy reccurent colorectal cancer (CRC).

Material and methods: The study covered 53 patients with CRC 21 males and 32 females at a mean age of 62 years treated in the Clinic of Liver, Biliary, Pancreatic and General Surgery, Tokuda Hospital of Sofia, during the period from January 2007 to March 2013. Any necessary diagnostic and surgical methods were applied.

Results: The locally recurrent CRC is a challenge for the surgeon because of the fact that in most cases it engages adjacent anatomical structures and organs, on the one hand, and it is accompanied by complications, on the other hand.

Conclusion: Achievement of good late results in patients with recurrent CRC is due to radicality of the interventions. Most often, they should be multivisceral resections. The presence of intestinal obstruction of varying degree and of synchronous peritoneal and liver metastases commonly limit the possibilities for surgical interference with the disease. Particular attention should be paid to possible neoadjuvant treatment capable of reducing the stage of diasease and improving the perioperative outcomes. Therapeutic behaviour should be strictly individual and consider any possible options. The experience of the surgical team is extremely important, too.


Keywords

colorectal cancer; adenocarcinoma; locally recurrent tumour; multivisceral resection; perioperative outcomes

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References

Adloff, M., J. P. Arnaud, M. Schloegel, D.

Thibaud. Factors influencing local recurrence

after abdominoperineal resection for cancer of

the rectum.- Dis. Colon Rectum, 28, 1985, No 6,

-415.

Bowne, W. B., B. Lee, W. D. Wong, L. Ben-Porat, J.

Shia, A. M. Cohen, et al. Operative salvage for

locoregional recurrent colon cancer after curative

resection: an analysis of 100 cases.- Dis. Colon

Rectum, 48, 2005, No 5,897-909.

Galandiuk, S., H. S. Wieand, C. G. Moertel, S. S.

Cha, R. J. Fitzgibbons, Jr., J. H. Pemberton, et al.

Patterns of recurrence after curative resection of

carcinoma of the colon and rectum.- Surg. Gynecol.

Obstet., 174, 1992, No 1, 27-32.

Guillem, J., L. Ruo. Strategies in operative therapy

for locally recurrent rectal cancer.- Semin. Colon

Rectal Surg., 9, 1998, 259-268.

Hartley, J. E., R. A. Lopez, P. B. Paty, W. D. Wong,

A. M. Cohen, J. G. Guillem. Resection of locally

recurrent colorectal cancer in the presence of

distant metastases: can it be justified?- Ann. Surg.

Oncol., 10, 2003, No 3, 227-233.

Hellinger, M. D., C. A. Santiago. Reoperation for

recurrent colorectal cancer.- Clin. Colon Rectal

Surg., 19, 2006, No 4, 228-236.

Maetani, S., T. Nishikawa, Y. Iijima, T. Tobe, Y.

Kotoura, J. Shikata. Extensive en bloc resection

of regionally recurrent carcinoma of the rectum.-

Cancer, 69, 1992, No 12, 2876-2883.

Mannaerts, G. H., H. J. Rutten, H. Martijn,

P. E. Hanssens, T. Wiggers. Comparison of

intraoperative radiation therapy-containing

multimodality treatment with historical treatment

modalities for locally recurrent rectal cancer.- Dis.

Colon Rectum, 44, 2001, No 12, 1749-1758.

Moore, H. G., M. Shoup, E. Riedel, B. D. Minsky, K.

M. Alektiar, M. Ercolani,, et al. Colorectal cancer

pelvic recurrences: determinants of resectability.-

Dis. Colon Rectum, 47, 2004, No 10, 1599-1606.

Obrand, D. I., P. H. Gordon. Incidence and patterns

of recurrence following curative resection for

colorectal carcinoma.- Dis. Colon Rectum, 40, 1997,

No 1, 15-24.

Pilipshen, S. J., M. Heilweil, S. H. Quan, S.

S. Sternberg, W. E. Enker. Patterns of pelvic

recurrence following definitive resections of rectal

cancer.- Cancer, 53, 1984, No 6, 1354-1362.

Read, T. E., M. G. Mutch, B. W. Chang, M. S.

McNevin, J. W. Fleshman, E. H. Birnbaum, et al.

Locoregional recurrence and survival after curative

resection of adenocarcinoma of the colon.- J. Am.

Coll. Surg., 195, 2002, No 1, 33-40.

Rich, T. A., N. H. Terry, M. Meistrich, K. Cleary,

D. Ota. Pathologic, anatomic, and biologic factors

correlated with local recurrence of colorectal

cancer.- Semin. Radiat. Oncol., 3, 1993, No 1,13-19.

Rödel, C., G. G. Grabenbauer, K. E. Matzel,

C. Schick, R. Fietkau, T. Papadopoulos, et al.

Extensive surgery after high dose preoperative

chemoradiotherapy for locally advanced recurrent

rectal cancer.- Dis. Colon Rectum, 43, 2000, No 3,

-319.

Sagar, P. M., J. H. Pemberton. Surgical management

of locally recurrent rectal cancer.- Br. J. Surg., 83,

, No 3, 293-304.

Shibata, D., P. B. Paty, J. G. Guillem, W. D.

Wong, A. M. Cohen. Surgical management of

isolated retroperitoneal recurrences of colorectal

carcinoma.- Dis. Colon Rectum, 45, 2002, No 6,

-801.

Shumate, C. R., T. A. Rich, J. M. Skibber, J. A.

Ajani, D. M. Ota. Preoperative chemotherapy and

radiation therapy for locally advanced primary and

recurrent rectal carcinoma.- Cancer, 71, 1993,

No 11, 3690-3696.

Taylor, W. E., J. H. Donohue, L. L. Gunderson,

H. Nelson, D. M. Nagorney, R. M. Devine, et al.

The Mayo Clinic experience with multimodality

treatment of locally advanced or recurrent colon

cancer.- Ann. Surg. Oncol., 9, 2002, No 2, 177-185.

Waldron, R. P., I. A. Donovan. Clinical follow

up and treatment of locally recurrent colorectal

cancer.- Dis. Colon Rectum, 30, 1987, No 6,

-430.




DOI: http://dx.doi.org/10.14748/ssm.v45i0.872

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About The Authors

V. Marinov
Tokuda Hospital of Sofia
Bulgaria

Clinic of Liver, Biliary, Pancreatic and General Surgery

R. Gaydarski
Tokuda Hospital of Sofia
Bulgaria

Clinic of Liver, Biliary, Pancreatic and General Surgery

K. Draganov
Tokuda Hospital of Sofia
Bulgaria

Clinic of Liver, Biliary, Pancreatic and General Surgery

N. Katev
Tokuda Hospital of Sofia
Bulgaria

Clinic of Liver, Biliary, Pancreatic and General Surgery

D. Rusenov
Tokuda Hospital of Sofia
Bulgaria

Clinic of Liver, Biliary, Pancreatic and General Surgery

Y. Kolev
Tokuda Hospital of Sofia
Bulgaria

Clinic of Liver, Biliary, Pancreatic and General Surgery

A. Petreska
Tokuda Hospital of Sofia
Bulgaria

Clinic of Liver, Biliary, Pancreatic and General Surgery

B. Borisov
Tokuda Hospital of Sofia
Bulgaria

Clinic of Liver, Biliary, Pancreatic and General Surgery

G. Chengalova
Tokuda Hospital of Sofia
Bulgaria

Clinic of Liver, Biliary, Pancreatic and General Surgery

S. Lavchev
Tokuda Hospital of Sofia
Bulgaria

Clinic of Liver, Biliary, Pancreatic and General Surgery

D. Penchev
Tokuda Hospital of Sofia
Bulgaria

Clinic of Liver, Biliary, Pancreatic and General Surgery

D. Stoyanova
Tokuda Hospital of Sofia
Bulgaria

Clinic of Liver, Biliary, Pancreatic and General Surgery

S. Tonev
Tokuda Hospital of Sofia
Bulgaria

Clinic of Liver, Biliary, Pancreatic and General Surgery

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