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Primary temporomandibular disorders and comorbid conditions

Vassil Svechtarov, Savina Nencheva - Svechtarova


INTRODUCTION:The aim of this study is to evaluate the distribution of the most common comorbid conditions associated with chronic temporomandibular disorders, and the Pharmacological agents which play an integral role in the overall management of temporomandibular joint disorders.


MATERIAL AND METHODS: A total of 23 articles are included in this comprehensive review of the relevant studies on common comorbid conditions related to temporomandibular disorders. This review provides summarized clinical and online platform based analyses focused on five most common comorbid conditions and its relevant pharmacological therapy.


RESULTS AND CONCLUSION: The majority of the studies show that comorbid conditions may include fibromyalgia, systemic myofascial pain and chronic fatigue syndrome, chronic headaches, migraine, heart arrhythmias, endometriosis, interstitial cystitis, irritable bowel syndrome, low back pain, sleep disorders - insomnia, autoimmune diseases, sleep apnea, noises and irritation in the ear, vulvodynia and mental disorders.The top comorbid conditions reported from people with TMJ syndrome, regardless of status are: anxiety, depression, insomnia, fatigue and pain. 


comorbid conditions, temporomandibular disorders, pharmacological agents

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About The Authors

Vassil Svechtarov
Medical University of Sofia

Associate Professor, Department OMFS

Savina Nencheva - Svechtarova
Medical University of Sofia


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