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Scripta Scientifica Pharmaceutica

A quartz crystal microbalance-assisted method for the assessment of iodine content in organoiodines

Iliyan Nikolov Kolev, Pavlina М Koseva, Mihail K Marinov, Gergana Е Alexieva, Vesselin L Strashilov

Abstract

Introduction: A new experimental quantitative approach for evaluating iodine content in organoiodine compounds has been proposed, based on the quartz crystal microbalance (QCM) method. This approach relies on following the time behavior of the resonance frequency of the quartz plate under temperature activation of iodine-containing analyte deposited on its surface.

Materials and Methods: We have applied the QCM method and the pharmacopoeial titrimetric method.

Results and Conclusion: From the mass variations observed, the quantity of emitted iodine is precisely obtained, which readily delivers its initial content in the studied sample. The obtained value corresponds exactly to the theoretical prediction, in contrast to the value obtained by applying the conventional pharmacopoeial metrics.


Keywords

iodine content, organoiodine compounds, QCM

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References

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DOI: http://dx.doi.org/10.14748/ssp.v5i2.5629

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About The Authors

Iliyan Nikolov Kolev
https://scholar.google.com/citations?user=lK92M58AAAAJ&hl=en
Medical University of Varna
Bulgaria

Department of Pharmaceutical Chemistry, Faculty of Pharmacy

Pavlina М Koseva
Medical University of Varna
Bulgaria

Department of Pharmaceutical Chemistry, Faculty of Pharmacy

Mihail K Marinov
Freelance electronics engineer, Varna
Bulgaria

Gergana Е Alexieva
Sofia University "St. Kl. Ohridski"
Bulgaria

Department of Solid State Physics and Microelectronics, Faculty of Physics

Vesselin L Strashilov
Sofia University "St. Kl. Ohridski"
Bulgaria

Department of Solid State Physics and Microelectronics, Faculty of Physics

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