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Arterial spin labeling MRI - clinical applications

Emilian Kalchev, Radoslav Georgiev, Boyan Balev


Arterial spin labeling (ASL) is a modern magnetic-resonance technique for evaluation of brain perfusion. One of its most important advantages is that there is no need for an injection of an exogenous contrast material. ASL generates an image by magnetically `labeling` water molecules in arterial vessels. Thus, ASL is an alternative to the invasive techniques requiring intravenous contrast medium, and in some cases, it even proves to be a better choice. There is a wide clinical application for ASL, ranging from stroke, brain neoplasms and vascular malformations, to neurodegenerative and psychiatric disorders.


MRI; ASL; perfusion; stroke; cerebrovascular disease; dementia

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