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Annual for Hospital Pharmacy

Estimating the requirement for manipulation of medicines to provide accurate doses for children

A. Nunn, R. Richey, U. Shah, C. Barker, J. Craig, M. Peak, J. Ford, M. Turner

Abstract

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References

Waller DG Off-label and unlicensed prescribing for children: have we made any progress? Br J Clin Pharmacol 2007;64:1-2. doi:10.1111/ j.1365-2125.2007.02987.x

Richey RH, Donnell C, Shah UU, et al. An investigation of drug manipulation for dose accuracy in paediatric practice: the MODRIC study. Arch Dis Child 2011;96:e1. doi:10.1136/adc.2011.211243.20

Tan E, Cranswick NE, Rayner CR, et al. Dosing information for paediatric patients: are they really `therapeutic orphans`? Med J Aust 2003;179:195-8.

Paparella S Identified safety risks with splitting and crushing oral medications. J Emerg Nurs 2010;36:156-7.

Prot S, Fontan JE, Alberti C, et al. Drug administration errors and their determinants in pediatric in-patients. Int J Qual Health Care 2005;17:381-9.

Uppal N, Yasseen B, Seto W, et al. Drug formulations that require less than 0.1 mL of stock solution to prepare doses for infants and children. CMAJ 2011;183: E246-8.

Skwierczynski C, Conroy S How long does it take to administer oral medicines to children? Paediatr Perinat Drug Ther 2008;8:145-9.

Richey RH, Craig JV, Shah UU, et al. The manipulation of drugs to obtain the required dose: systematic review protocol. J Adv Nurs 2011;68:2103-12.

Rosenzweig EB, Ivy DD, Widlitz A, et al. Long-term bosentan treatment in children with pulmonary arterial hypertension. J Am Coll Cardiol 2006;47:1915.

Horn L, Kuhn RJ, Kanga JF Evaluation of the reproducibility of tablet splitting to provide accurate doses for the pediatric population. J Pediatr Pharm Pract 1999;4:38-42.

Shah RB, Collier JS, Sayeed VA, et al. Tablet splitting of a narrow therapeutic index drug: a case with levothyroxine sodium. AAPS PharmSciTech 2010;11:1359-67.

Broadhurst EC, Ford JL, Nunn AJ, et al. Dose uniformity of samples prepared from dispersible aspirin tablets for paediatric use. Eur J Hosp Pharm Sci 2008;14:27-31.

Verrue C, Mehuys E, Boussery K, et al. Tablet-splitting: a common yet not so innocent practice. J Adv Nurs 2011;67:26-32.

Kim TW, Rognerud CL, Ou C-N Accuracy in the alteration of acetaminophen suppositories. Anesth Analg 2005;100:1303-5.

Beringer RM, Thompson JP, Parry S, et al. Intravenous paracetamol overdose: two case reports and a change to national treatment guidelines. Arch Dis Child 2011;96:307-8.

Chappell K, Newnam C Potential tenfold drug overdoses on a neonatal unit. Arch Dis Child Fetal Neonatal Ed 2004;89:F483-4.

Allegaert K, Anderson BJ, Vrancken M, et al. Impact of a paediatric vial on the magnitude of systematic medication errors in neonates. Paed Perinat Drug Ther 2006;7:59-63.

Anon Intravenous paracetamol (Perfalgan): risk of accidental overdose, especially in infants and neonates. Drug Saf Update 2010;3:2. http://www.mhra.gov.uk/ Safetyinformation/DrugSafetyUpdate/CON088171 (accessed 4 Aug 2012).

British National Formulary for Children 2010-2011. London: BMJ Group, Pharmaceutical Press, RCPCH Publications, 2010.

Caldwell N, Rackham O Children`s doses should be measurable (letter). Arch Dis Child 2010;95:313.

World Health Organization (WHO). Antiretroviral therapy for HIV infection in infants and children: towards universal access. Recommendations for a public health approach: 2010 revision. Geneva: WHO, 2010. http://www.who.int/hiv/pub/ paediatric/infants2010/en/index.html (accessed 6 Oct 2011).

European Parliament. Regulation (EC) No 1901/2006 of the European Parliament and of the Council of 12 December 2006 on medicinal products for paediatric use. Official Journal of the European Union 27/12/2006:L378/1-19. http://ec.europa.eu/ health/files/eudralex/vol-1/reg_2006_1901/reg_2006_1901_en.pdf (accessed 6 Oct 2011).




DOI: http://dx.doi.org/10.14748/.v1i1.1882

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