The nerve growth factor (NGF) has been discovered by Rita Levi-Montalcini in the early 1950s. This paradigmic cell growth factor has gradually attracted the attention of many investigators from all over the world. In the very beginning, experimental research prevailed taking into consideration the still rather fundamental approach to the possible role of NGF and the subsequently discovered other neurotrophic factors in the living organism. Later on, an increasingly stable orientation of the scientific community towards the human beings, including a more outlined clinical research policy, has been emerging.
Biomedical Reviews 1999; 10: 107-110.
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