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Biomedical Reviews

In the heart of adipobiology: cardiometabolic disease

George N. Chaldakov, Marco Fiore, Anton B. Tonchev, Gorana Rančić, Mariyana G. Hristova, Neşe Tunçel, Dimitar D. Kostov, Vesselka Nikolova, Vladmila Bojanić, Luigi Aloe

Abstract

Published on 1 December 1994 issue of Nature, the Jeffrey Friedman's discovery "gave leptin in the beginning" of the endocrine saga of adipose tissue. Onwards, studies on this tissue have enjoyed an explosive growth that conceptualized a novel field of research, adipobiology. Arguably, in the heart of adipobiology and adipopharmacology are studies focusing on the pathogenesis, prevention and therapy of cardiometabolic diseases (CMD) including atherosclerosis, hypertension, obesity, type 2 diabetes, metabolic syndrome (global cardiometabolic risk), and lipodystrophies.

Biomedical Reviews 2009; 20: 1-5.


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DOI: http://dx.doi.org/10.14748/bmr.v20.49

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About The Authors

George N. Chaldakov
Medical University of Varna
Bulgaria

Marco Fiore
National Research Council of Rome
Italy

Anton B. Tonchev
Medical University of Varna
Bulgaria

Gorana Rančić
University of Niš
Serbia

Mariyana G. Hristova
Private Endocrinology Consulting Office of Varna
Bulgaria

Neşe Tunçel
Eskisehir Osmangazi University
Turkey

Dimitar D. Kostov
University St Marina Hospital of Varna
Bulgaria

Vesselka Nikolova
Medical University of Varna
Bulgaria

Vladmila Bojanić
University of Niš
Serbia

Luigi Aloe
National Research Council of Rome
Italy

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