Blobel G. Protein targeting. Biosci Rep 2000;20:303- 344. doi: 10.1023/a:1010318832604
Cecconi A, Vilchez-Tschischke JP, Mateo J, Sanchez
Gonzalez J, España S, et al. (2021) Effects of colchicine on atherosclerotic plaque stabilization: a multimodality imaging study in an animal model. J Cardiovasc Transl Res 14(1):150-160. doi:10.1007/s12265-020-09974-7
Chaldakov GN, Nikolov SD (1975) Ultrastructure of the arterial smooth muscle cell. In: Wolf S, Werthessen NT, editors. The Smooth Muscle of the Artery. New York City, NY: Plenum Press. Adv Exp Med Biol 57:14-20.
Chaldakov GN, Nikolov S, Vancov V (1977) Fine morphological aspects of the secretory process in arte- rial smooth muscle cells. II. Role of microtubules. Acta Morphol Acad Sci Hung 25:167-174.
Chaldakov GN, Kádár A (1978) Microtubules in arterial smooth muscle cells in vivo and in tissue culture. An electron microscope study. In: W. Hauss, R. Wissler, R. Lehman, editors. State of Prevention and Therapy of Human Arteriosclerosis and in Animal Models. Rheinisch-Westfalische Akad. Der Wissenschaften, p. 211- 231.
Chaldakov G. GEORGE E. PALADE LECTURE. Human body as a multicrine system, with special reference to cell protein secretion: from vascular smooth mus- cles to adipose tissue. Adipobiology 2016;8:6-18. doi: 10.14748/adipo.v8.2089
Chaldakov G, Stankulov I, Hristova M, Ghenev P. Adipobiology of disease: Adipokines and adipokine-targeted pharmacology. Curr Pharm Des 2003; 9: 1023-1031. doi: 10.2174/1381612033455152
Chaldakov GN (1982) Antitubulins - a new therapeutic
approach for atherosclerosis? Atherosclerosis 44:385- 390. doi: 10.1016/0021-9150(82)90013-2
Chaldakov GN (2018) Colchicine, a microtubule-disassembling drug, in the therapy of cardiovascular diseases. Cell Biol Int 42:1079-1084. doi: 10.1002/cbin.10988
Chaldakov GN, Beltowsky J, Ghenev PI, Fiore M, Pa-
nayotov P, Rančič G, Aloe L Adipoparacrinology - vascular periadventitial adipose tissue (tunica adiposa) as an example. Cell Biol Int 2012;36:327-330. doi: 10.1042/cbi20110422
Chaldakov GN, Fiore M (2010) Human body as a multicrine gland. Adipobiology 2: 73-75. doi: 10.14748/ adipo.v2.263
Chaldakov GN, Vankov VN (1986a) Morphological
aspects of secretion in the arterial smooth muscle cell, with special reference to the Golgi complex and micro- tubular cytoskeleton. Atherosclerosis 61: 175-192. doi:
1016/0021- 9150(86)90137-1
Chaldakov GN, Aloe L, Kádár A, Ghenev P, Fiore M, Pancheva RZ, et al. (2021) Homage to George E. Pal- ade. Cell protein secretion in vascular biology: over- view and updates. ABMJ 4(1): 31-43. doi: 10.2478/abmj-2021-0004
Chaldakov GN, Zhelyazkova-Savova MD, Panayotova D, Fiore M, Yanev S. Phenotypic modulation of smooth muscle cells and matrix metalloproteinases as targets for atherosclerotic plaque stabilization. Biomed Rev 2020;31: 49-60. doi: 10.14748/bmr.v31.7704
Chaldakov GN (2022) Principles of Cell Biology.
BioMedES Ltd, Aberdeen, United Kingdom. Avail- able in Amazon.com https://www.amazon.com.au/ Principles-Cell-Biology-George-Chaldakov-ebook/dp/ B0BKWHKVWP
Farquhar MG. A Man for all seasons: Reflections on the
life and legacy of George Palade. Ann Rev Cell Dev Biol
;28: 1-28. doi: 10.1146/annurev-cellbio-101011-155813
Farquhar MG, Palade GE (1998) The Golgi apparatus: 100 years of progress and controversy. Trends Cell Biol 8:2-10. doi: 10.1016/S0962-8924(97)01187-2
Frohlich J, Chaldakov GN, Vinciguerra M (2021) Cardio- and neurometabolic adipobiology: Consequences and implications for therapy. Int J Mol Sci 22: 4137. doi: 10.3390/ ijms22084137
Ghenev PI, Aloe L, Kisheva AR, Singh M, Panayotov
P, Fiore M, et al. (2017) QUO VADIS, ATHEROGENESIS? Part 1. Smooth muscle cell secretion – how foe becomes friend in the fight against the atherosclerotic plaque. Biomed Rev 28:134-138.
Haust MD, More RH, Movat HZ (1960) The role of smooth muscle cells in the fibrogenesis of arteriosclero- sis. Am J Pathol 37:377-389.
Jena BP (2010) Porosome: the universal secretory portal in cells. Biomed Rev 21: 1- 15. doi: 10.14748/bmr. v21.42
Lai CP, Breakefield XO (2012) Role of exosomes/microvesicles in the nervous system and use in emerging therapies. Front Physiol 3: 228. doi: 10.3389/ fphys.2012.00228
Lee JZ, Singh N, Howe CL, Low S-W, Huang JJ, Ortega G, et al. (2016) Colchicine for prevention of post- operative atrial fibrillation. A meta-analysis. J Am Coll Cardiol Clin Electrophyisol 2(1): 78-85. doi: https://doi. org/10.1016/j.jacep.2015.09.016
Libby P (2021) Inflammation in atherosclerosis - No longer a theory. Clin Chem 67:131-142. doi:10.1093/clinchem/hvaa275
Mazzarello P, Garbarino C, Calligaro A (2009) How
Camillo Golgi became “the Golgi”. FEBS Lett 583: 3732-3737. doi: 10.1016/j.febslet.2009.10.018
Mullen M, Jin XY, Child A, Stuart AG, Dodd M, Aragon-Martin JA, et al. (2019) Irbesartan in Marfan syndrome (AIMS): a double-blind, placebo-controlled randomised trial. Lancet 394: 2263–2270. doi: 10.1016/ S0140-6736(19)32518-8
Nickel W (2010) Pathways of unconventional protein secretion. Curr Opin Biotechnol 21: 621-626. doi: 10.1016/j.copbio.2010.06.004
Nidorf SM, Eikelboom JW, Budgeon CA, Thompson PL (2013) Low-dose colchicine for secondary prevention of cardiovascular disease. J Am Coll Cardiol 61(4):404- 410. doi: 10.1016/j.jacc.2012.10.02
Palade G (1975) Intracellular aspects of the process of
protein synthesis. Science 189: 347-358. doi: 10.1126/science.1096303
Palade GE (1971) Albert Claude and the beginnings of
biological electron microscopy. J Cell Biol 50: 5d-19d. doi: 10.1083/jcb.50.1.5d
Ross R (1999) Atherosclerosis - An inflammatory disease. N Engl J Med 340: 115-126. doi: 10.1056/nejm199901143400207
Sadallah S, Eken C, Martin PJ, Schifferli JA (2011) Microparticles (ectosomes) shed by stored human platelets downregulate macrophages and modify the development of dendritic cells. J Immunol 186: 6543- 6552. doi: 10.4049/jimmunol.1002788
Shankman LS, Gomez D, Cherepanova OA, Salmon M,
Alencar GF, Haskins RM, et al. (2015) KLF4-depend- ent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis. Nat Med 21(6): 628-637. doi: 10.1038/nm.3866
Silver R, Pappas G (2005) Secretion without membrane
fusion: Porocytosis. Anat Rec B New Anat 282: 18-37. doi: 10.1002/ar.b.20050
Singer MV (2003) Legacy of a distinguished scientist: George E. Palade. Pancreatology 3:518–519. doi: 10.1159/000076328
Tardif J-C, Kouz S, Waters DD, Bertrand OF, Diaz R,
Maggioni AP, et al. (2019) Efficacy and safety of low- dose colchicine after myocardial infarction. N Engl J Med 381(26):2497-2505.
doi: 10.1056/NEJMoa1912388
Töre F, Tonchev A, Fiore M, Tunçel N, Atanassova P, Aloe L, et al. (2007) From adipose tissue protein secretion to adipopharmacology of disease. Immun Endoc Metab Agents Med Chem 7: 149- 155. doi: 10.2174/187152207780363712
Vaidya K, Arnott C, Martínez GJ, Ng B, McCormack S,
Sullivan DR, et al. Colchicine therapy and plaque stabilization in patients with acute coronary syndrome. J Am Coll Cardiol Img 2017; doi: https://doi.org/10.1016/j. jcmg.2017.08.013
Wirka RC, Wagh DA, Paik DT, et al. (2019) Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis. Nat Med 25(8): doi:10.1038/ s41591-019-0512-5
Yanev S, Fiore M, Hinev A, Ghenev PI, Hristova MG, Panayotov P, et al. (2016) From antitubulins to trackins. Biomed Rev 27:59-67.
Zar M, Amadio P, Campodonico J, et al. (2020) Ex- osomes in cardiovascular diseases. Diagnostics 10:943. doi:10.3390/diagnostics1011094
Email this article (Login required) 
