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Assessing the Effectiveness of qSOFA and SIRS Scoring Systems:t a Single-Center

Pavlina Peneva, Yana Bocheva, Silviya P. Nikolova

Abstract

In the context of post-2016 redefinitions of sepsis and septic shock, this prospective, non-interventional single-center clinical trial was carried out at St. Marina University Hospital, Varna, Bulgaria. The study encompassed 87 participants, approximately 45 of whom presented with sepsis and septic shock. Employing logistic regression, the study aimed to assess the predictive value of the Systemic Inflammatory Response Syndrome (SIRS) and quick Sequential Organ Failure Assessment (qSOFA) criteria in sepsis. Additionally, sensitivity and specificity were evaluated using ROC curve analysis. The findings revealed the substantial predictive potential of both SIRS and qSOFA for septic patient mortality. Notably, the qSOFA score exhibited a significantly higher likelihood (2.581 times, p = 0.0001, 95% CI 1.557 - 4.279) of predicting mortality compared to the SIRS scale (2.050-fold, p = 0.004, 95% CI 1.255 - 3.349). The study contributes to guiding the enhancement of patient care strategies, effortlessly aligning with the core tenets of evidence-based nursing practices.

Keywords

SIRS, qSOFA, SOFA, National Early Warning Score, Sepsis, Mortality, Predictability

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DOI: http://dx.doi.org/10.14748/bmr.v34.9626

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About The Authors

Pavlina Peneva
First Department of Internal Diseases, UMHAT St. Marina, Medical University, Varna, Bulgaria

Yana Bocheva
Clinical Laboratory, UMHAT St. Marina, Medical University, Varna, Bulgaria

Silviya P. Nikolova
Department of Social Medicine and Healthcare Organization, Medical University, Varna, Bulgaria

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