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Bulgarian Review of Ophthalmology

Application of Rarebit Perimetry in Preperimetric Glaucoma

M. Benova, V. Shumnalieva, Y. Zdravkov, I. Tanev


Aim: То determine the diagnostic capabilities of Rarebit perimetry for detection of early functional changes in primary open-angle glaucoma.

Methods: А total of 47 eyes divided into two groups: 23 eyes with preperimetric glaucoma (PPG) and a control group of 24 eyes were examined with Rarebit perimetry (RBP) and standard automated perimetry (SAP). То evaluate the differences between the groups were used Kruskal Wallis Test, Mann-Whitney Test and Fisher's Exact Test. The sensitivity and specificity of the RBP for detection of early glaucomatous changes were evaluated by ROC analysis using different algorithms.

Results: Average МНR for control and PPG group were respectively: 94.71% (SD 2.58); 87.61% (SD 4.80). Differences in МНR between the groups were statistically significant (Мann-Whitney Test, р <0.001). The highest value of AROC (0.849) was achieved when as abnormal was accepted Rarebit test with МНR <90% when comparing healthy eyes to those with PPG.

Conclusion: RBP is sensitive method for visual field defects in preperimetric glaucoma. The test is quick and easy to perform.


standard automated perimetry; Rarebit perimetry; sensitivity; specificity

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About The Authors

M. Benova


V. Shumnalieva
Department of Ophthalmology, Medical University, `Alexandrovska` Hospital, Sofia

Y. Zdravkov
Department of Ophthalmology, Medical University, `Alexandrovska` Hospital, Sofia

I. Tanev
Department of Ophthalmology, Medical University, `Alexandrovska` Hospital, Sofia