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Bulgarian Review of Ophthalmology

Mean Age of Patients with and without Type 2 Diabetes Mellitus during Surgical Treatment of Age-Related Cataract

V. Haykin, Y. Zdravkov, S. Kostova, V. Dimitrova, A. Isaeva, A. Oscar

Abstract

Introduction: Age-related cataract is one of the most common causes of preventable blindness. Type 2 diabetes is a non-infectious epidemic disease with an ever-increasing number of diseased patients. Cataract is one of the leading causes of reduced vision in diabetics. The preferred treatment method is phacoemulsification. The aim of the present study was to compare the mean age of patients with and without diabetes type 2 at the time of cataract surgery. Materials and methods: After informed consent and approval by the Ethics Commission of the Medical University of Sofia, 176 patients admitted to the Clinic of Ophthalmology at the University Hospital „Alexandrovska“ for surgical treatment of cataract were randomized. Inclusion criteria: diagnosed age-related cataract, requiring surgical treatment. Patients were divided into two groups – diabetic type 2 and non-diabetic patients. Inclusion criteria for the group of diabetics: medical history of diabetes type 2 and administration of anti diabetic medications. Results: The average age of patients undergoing cataract surgery was 70.81 years. The average ageof patients with diabetes type 2 was 65.89 years, and that of non-diabetics – 71.74 years. Diabetes type 2 was established at 15.91 % of patients (19 men and 9 women). Conclusion: Patients with diabetes type 2 develop age-related cataract, requiring surgical treatment, at an earlier age compared to non-diabetics. The transparency of the lens in diabetic patients is of particular importance for the diagnosis and treatment of the diabetic retinopathy. Follow-up by an ophthalmologist and maintenance of strict blood glucose control are necessary to reduce the incidence of vision loss, caused by cataract and diabetic retinopathy.


Keywords

cataract, diabetes mellitus

Full Text


References

Здравков Я, Янкова Е, Цветкова Г, et al. Предиктивни фактори за развитие на постоперативна фибринова ексудация. Български офталмологичен преглед, 2018;62(1): 33-42.

Nam SW, Lim DH, Cho KY, et al. Risk Factors of Presenile Nuclear Cataract in Health Screening Study. BMC Ophthalmology. 2018;18(1):1-9.

Георгиева А, Петкова И. Диабет и очни усложнения. Диабет и метаболизъм, 2014;4:3-7.

Pollreisz A, Schmidt-Erfurth U. Diabetic Cataract – Pathogenesis, Epidemiology and Treatment. J Ophthalmol, 2010:1-8.

Kumamoto Y, Takamura Y, Kubo E, et al. Epithelial Cell Density in Cataractous Lenses of Patients with Diabetes: Association with Erythrocyte Aldose Reductase. Experimental Eye Research, 2007;85(3):393-399.

Srivastava SK, Ramana KV, Bhatnagar A. Role of Aldose Reductase and Oxidative Damage in Diabetes and the Consequent Potential for Therapeutic Options. Endocrine Reviews, 2005;26(3):380-392.

Leske MC, Wu SY, Hennis A, et al. Diabetes, Hypertension, and Central Obesity as Cataract Risk Factors in a Black Population. Ophthalmology, 1999;106(1):35-41.

Pessoa R, Lira C, Nascimento MA, et al. Incidence of Preoperative High Blood Pressure in Cataract Surgery among Hypertensive and Normotensive Patients. Indian J Ophtalmol, 2010;58(6):493-495.

Haykin V, Oscar A, Dimitrova, et al. Bioimage Analysis of Cell Physiology of Primary Lens Epithelial Cells from Diabetic and Non-Diabetic Cataract Patients. Biothechnology&Biotechnological Equipment, 2021;35(1): 170-178.

Minckler D. Cataract Surgery in Patients with Diabetes. Ophthalmology, 1998;105(6): 949-950.

Obrosova IG, Chung SSM, Kador PF. Diabetic Cataracts: Mechanisms and Management. Diabetes Metab. Res. Rev, 2010;26(3):172-180.

Memon A, Mahar P, Memon M, et al. Age-Related Cataract and Its Types in Patients with and without Type 2 Diabetes Mellitus: A Hospital-Based Comparative Study. JPMA. J Pakistan Med Association, 2016;66: 1272-1276.

Kelkar A, Kelkar J, Mehta H, Amoaku W. Cataract Surgery in Diabetes Mellitus: A Systematic Review. Indian J Ophthalmol, 2018;66(10):1401-1410.




DOI: http://dx.doi.org/10.14748/bro.v65i3.8127

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About The Authors

V. Haykin
MU – Sofia
Bulgaria

Department of Ophthalmology

University Hospital „Alexandrovska“, Clinic of Ophthalmology

Y. Zdravkov
MU – Sofia
Bulgaria

Department of Ophthalmology

University Hospital „Alexandrovska“, Clinic of Ophthalmology

S. Kostova
MU – Sofia
Bulgaria

Department of Ophthalmology

University Hospital „Alexandrovska“, Clinic of Ophthalmology

V. Dimitrova
MU – Sofia
Bulgaria

Department of Medical Chemistry and Biochemistry

A. Isaeva
MU – Sofia
Bulgaria

Department of Medical Chemistry and Biochemistry

A. Oscar
MU – Sofia
Bulgaria

Department of Ophthalmology

University Hospital „Alexandrovska“, Clinic of Ophthalmology

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