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Bulgarian Review of Ophthalmology

Ophthalmic Status of Newborn Children at Risk – Preliminary Results

G. Tsvetkova, A. Oscar


Retinopathy of prematurity (ROP) is a leading cause of low vision and preventable blindness among the pediatric population with gestational age, birth weight, stage of retinopathy as well as the need and type of treatment being of crucial significance. Purpose: To present preliminary results of the ophthalmic examination of newborn children at risk (with low and extremely low weight, preterm gestational age at birth), as to follow up the occurrence or absence of changes in the ophthalmic status of those with or without diagnosed ROP. Patients and methods: In the current study are participating 112 eyes of 56 children (24 boys and 32 girls), examined between March 2021 and August 2021 at the Pediatric Ophthalmic Outpatient Care Center and the Pediatric Ophthalmic Department of the University Hospital Aleksandrovska. The complete ophthalmic exam included assessment of: visual acuity, orthoptic status, biomicroscopy, ophthalmoscopy, autorefractometry/skiascopy, optical coherence tomography. Results: The patients were divided into two main groups: with and without diagnosed ROP. 19 children (38 eyes) were included in the first group, and 37 children (74 eyes) – in the second. The mean age of the examined children was 66.9 months, the mean gestational age at birth – 28.2 weeks, and the mean weight – 1041.13 g. 11 of the patients with diagnosed ROP were also treated for the condition. 9 of the premature children with diagnosed ROP required prescription of an optical correction. 5 of the children show deviation of the orthoptic status. Optical coherence tomography was conducted in 11 of the children, 10 of whom showed pathological irregularities in the results. Conclusion: Our study confirms the high prevalence of refractive anomalies and deviations of the orthoptic status in patients diagnosed with ROP. The early screening, as well as the introduction and integration of follow-up programs are important for reduction of the organic, functional, social and psycho-emotional consequences of ROP.


retinopathy of prematurity, newborn children at risk, ophthalmic status, refraction, late complications

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About The Authors

G. Tsvetkova
Medical University ‒ Sofia

Department of Ophthalmology

University Clinic of Eye Diseases, University Hospital Aleksandrovska ‒ Sofia

A. Oscar
Medical University ‒ Sofia

Department of Ophthalmology

University Clinic of Eye Diseases, University Hospital Aleksandrovska ‒ Sofia