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Bulgarian Review of Ophthalmology

Regression after Laser Correction of Hyperopia

D. Mitova, T. MItov, M. Litev


Purpose: to analyse causative factors for regress in hyperopic laser vision correction. Materials and methods: Metaanalysis of the literature and retrospective analysis of 20 consecutive cases of recorrection at the St. Petka Eye Clinic Varna in the last year. Correlation with pre- and post- operative Kmax, pachimetry (center/periphery), nuclear sclerosis and dysfunctional lens syndrome, total ablation zone, optical zone, cycloplegic refraction, target refraction, age of the patient was done. Re-correction was done with re-lift in 18 of the patients and with re-cut in two of them. Results: Small optical and total ablation zone showed positive correlation with hyperopic regress, while flap diameter correlates as far it is linked to the total ablation zone. Positive correlation was found in thin corneas and in patients over 50 years of age. Discussion: Based on the analysis of the results, recommendations for operative protocol was elaborated in order to minimize the risk for regression post hyperopic LASIK.


regression, hyperopia, total zone, ablation zone, hysteresis

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Hashemi H, Fotouhi A, Yekta A et al. Global and regional estimates of prevalence of refractive errors: Systematic review and meta-analysis. J Curr Ophthalmol, 2017 Sep 27; 30 (1):3-22. doi:10.1016/j.joco.2017.08.009.

Moshirfar М, Comparison of Visual Outcome After Hyperopic LASIK Using a Wavefront-Optimized Platform Versus Other Excimer Lasers in the Past Two Decade. Ophthalmol Ther, 2021, 10:547-563

Moshirfar М et al. Mechanisms of Optical Regression Following Corneal Laser Refractive Surgery: Epithelial and Stromal Responses. Med Hypothesis Discov Innov Ophthalmol, 2018; 7(1).

Soler V et al. A randomized comparison of pupil-centered versus vertex-centered ablation in LASIK correction for Hypermetropia. Am J Ophthalmol, 2011, Oct;152(4):591-599.

Manche E, Sales C. One-year eye-to-eye comparison of wavefront-guided versus wavefront-optimized laser in situ keratomileusis in hyperopes. Clin Ophthalmol, 2014, 2229. doi:10.2147/opth.s70145.

Naderi et al. Studying the factors related to refractive error regression after PRK surgery. BMC Ophthalmology, 2018, 18:198.

Gharaibeh AM, Villanueva A, Mas D et al. Corneal Stability following Hyperopic LASIK with Advanced Laser Ablation Profiles, 2018.

Whang WJ, Yoo YS, Joo CK. Corneal power changes with Scheimpflug rotating camera after hyperopic LASIK. Medicine (Baltimore), 2018 Dec; 97(50):e13306. doi: 10.1097/MD.0000000000013306.

Li T, Zhou X, Chen Z et al. Corneal Thickness Profile Changes аfter Femtosecond LASIK for Hyperopia. Eye & Contact Lens: Science & Clinical Practice, 2017, 43, 297-301. doi:10.1097/icl.0000000000000279.

Frings A et al. Outcomes of retreatment after hyperopic laser in situ keratomileusis. J Cataract & Refractive Surgery, 2017, 43(11), 1436-1442. doi: 10.1016/j.jcrs.2017.08.014.

Wagh VK, Dave R, O’Brart D et al. Eighteen-year follow-up of hyperopic photorefractive keratectomy. J Cataract & Refractive Surgery, 2016, 42(2), 258-266. doi: 10.1016/j.jcrs.2015.09.025.

Settas G, Settas C, Minos E et al. Photorefractive keratectomy (PRK) versus laser assisted in situ keratomileusis (LASIK) for hyperopia correction. Cochrane Database Syst Rev, 2012 Jun 13; 2012(6):CD007112. doi:10.1002/14651858.CD007112.pub3.

Litev M, Voynov L, Mitov T et al. Causative factors for hyperopia regression in excimer keratorefractive surgery. Bulgarian Rev Ophthalmol, 2016, 60, 28. doi:10.14748/bro.v0i3.4550

Литев М, Войнов Л, Митов Т. Причини за регрес на хиперметропия след кераторефрактивна лазерна корекция, Мединфо, 2018, 18(2), 60-65.

Fatseas G, Stapleton F, Versace P. Role of percent peripheral tissue ablated on refractive outcomes following hyperopic LASIK, PLOS ONE, February 2, 2017, DOI:10.1371/journal.pone.0170559.

Aslanides and Mukherjee, Adjuvant corneal crosslinking to prevent hyperopic LASIK regression. Clin Ophthalmol, 2013:7 637-641.

Moawad Ehab M еt al. LASIK-induced corneal changes after correction of hyperopia with and without application of Mitomycin-C. BMC Ophthalmology, 2019, 19:93.

Taneri S, Hansson C. Reevaluating Hyperopic LASIK, CRST, Sept, 2021.



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About The Authors

D. Mitova
Eye Clinic Sveta Petka – Varna

Trakia University – Stara Zagora

T. MItov
Eye Clinic Sveta Petka – Varna

M. Litev
Eye Clinic Sveta Petka – Varna