Scientific Online Resource System

Conference Proceedings

Профилактика на инфекциите на пикочните пътища при деца до три годишна възраст чрез кърмене

Р. Чамова, T. Димитрова, Д. Близнакова


Introduction: Urinary tract infections (UTIs) are among the most common diseases in childhood. Their tendency to become chronic leads to a risk of severe renal impairment and of chronic kidney disease for children. Aim: The aim of this article is to discuss the protective effect of breastfeeding on the development of UTIs in infants and children in early childhood.

Materials and Methods: A case-control study was conducted in children under three years of age in Varna. The parents of 216 healthy children and of 108 children with UTIs were interviewed about breastfeeding practices and complementary feeding. The results of laboratory and ultrasound tests of the urinary system in the group of cases have been analyzed. For the statistical analysis SPSS (v.17.0) was used. Frequencies and descriptive analysis, χ2 test of Pearson, t-test of Student and correlation by Pearson were used. Statistical significance was determined at the level of significance p<0.05.

Results: The average age of patients and controls was 17.7 ± 1 months. Breastfed children suffering of UTIs were 87%. The median of the duration of breastfeeding and exclusive breastfeeding in the cases is respectively

3.5± and 0 months compared to the significantly longer duration of these periods in the controls - 6 months and 2 months (p<0.005). The mean age of initiation of complementary feeding among our respondents was 4.8±0.1 months.

Conclusion: Breast milk has a protective effect on UTIs in children up to 3 years of age.


breastfeeding; urinary tract infections; prevention

Full Text


Беловеждов, Н. Инфекциии на пикочните пътища и бъбреците. София: Тип Топ Прес, 2003

Близнакова, Д. За детската нефрология – практично. - Университетско изд. на МУ – Варна, Варна, 2015

Ушева, Н. Успешно кърмене и захранване на децата – съвременни тенденции, проблеми и възможности за решаването им. Автореферат на дисертационен труд за присъждане на образователна и научна степен

„доктор”. Варна, 2013

Agostoni, C, T. Decsi, M. Fewtrell et al. Complementary feeding: A commentary by the ESPGHAN Committee on Nutrition. J Pediatr Gastroenterol Nutr. 2008; 46: 99–110

Agostoni, C., C. Braegger, T. Decsi et al. Breastfeeding: A Commentary by the ESPGHAN Committee on Nutrition. Journal of Pediatric Gastroenterology and Nutrition. 2009: 49: 112-125

Cleper, R., I. Krause, B. Eisenstein, M. Davidovits. Prevalence of vesicoureteral reflux in neonatal urinary tract infection. Clin Pediatr (Phila). 2004; 43: 619-25

Gdalevich, M., D. Mimouni, M. David, M. Mimouni. Breast-feeding and the onset of atopic dermatitis in childhood: a systematic review and meta-analysis of prospective studies. J Am Acad Dermatol. 2001a; 45: 520– 527

Hanson, L. A. Protective effects of breastfeeding against urinary tract infection. Acta Paediatr. 2004; 93: 154–6

IOM (Institute of Medicine). Child and Adult Care Food Program: Aligning Dietary Guidance for All. Washington, DC: The National Academies Press 2011

Lucas, A., T. J. Cole. Breast milk and neonatal necrotising enterocolitis. Lancet. 1990; 336(8730): 1519–23

Oddy, W. H., P. D. Sly, N. H. de Klerk et al. Brestfeeding and respiratory morbidity in infancy: a birth cohort study. Arch Dis Child. 2003; 88: 224-228

Pisacane, A., L. Graziano, G. Mazzarella et al. Breastfeeding and urinary tract infection. J Pediatr. 1992; 120: 87- 9

Sabirov, A., J. R. Casey, T. F. Murphy, M. E. Pichichero. Breast-feeding is associated with a reduced frequency of acute otitis media and high serum antibody levels against NTHi and outer membrane protein vaccine antigen candidate P6. Pediatr Res. 2009; 66(5): 565-70

Shaikh, N., N. E. Morone, J. E. Bost et al. Prevalence of urinary tract infection in childhood: a meta-analysis. Pediatr Infect Dis J. 2008; 27: 302-8

Vilanova Juanola, J. M., J. Canos Molinos, E. Rosell Arnold, J. Figueras Aloy, L.L. Comas Masmitja, R. Jimenez Gonzalez. Urinary tract infection in the newborn infant. Pediatr. 1989; 31(2): 105-9

WHO. European Strategy for Child and Adolescent Health and Development. WHO Regional Office for Europe 2005

Zelikovic, I., R. D. Adelman, P. A. Nancarrow. Urinary tract infections in children. West J Med. 1992; 157(5):



Font Size