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Celiac Disease – Thе Old New Disease

Miglena Georgieva


Aretaeus from Cappadocia (2nd century AD) described chronic diarrhea with malabsorption in children and women, calling it a celiac disorder. Celiac disease is an immune-mediated systemic disorder caused by gluten and related prolamines in genetically predisposed individuals. The clinical manifestations are related to the digestive tract or are outside the digestive tract. Celiac disease is diagnosed with the help of a detailed medical history and physical examination; routine hematological and laboratory tests, specific serological tests, jejunal biopsy, abdominal ultrasound, X-ray methods, capsule endoscopy, specific genetic markers. The treatment includes a strict gluten-free diet for life, vitamins and micro- and macroelements, iron, vitamin B12, folic acid, vitamin D. The prognosis for patients with celiac disease with strict adherence to a gluten-free diet and strict monitoring is good.


celiac disease, children, chronic diarrhea, serological tests, gluten-free diet

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