Assessing health-related quality of life is an important step when understanding the disease of the patients. The most widely used assessment tool is the questionnaire for quality of life in patients with inflammatory bowel disease (IBD) (IBDQ 32). The purpose of this study is to evaluate the quality of life in 124 patients with IBD in one clinical center. Material and methods: 74 patients with ulcerative colitis (UC) and 50 with Chron`s disease (CD) participated in the study. To assess their quality of life we used IBDQ, which contains 32 questions that evaluate the emotional aspects, the disease, the social aspects of life and systemic symptoms. Descriptive analysis, comparative analysis and IBM SPSS v. 20 were used. Results: The overall quality of life is 151, 34 (52 - 222). There is no significant difference between patients with UC and those CD. The assessment of quality of life in terms of the extension of the disease showed a trend towards deterioration in quality. There was a significant difference in the overall score and in the social aspects. The patients with newly diagnosed IBD have an IBDQ of 146.40 ± 45.22. The results from the analysis show that the significant difference in the quality of life is proven when it comes to activity of the disease; patents in remission have the best quality of life and those with severe disease - the worst. Conclusion: The QL evaluation, made using the IBDQ, did not detect a significant difference in the QL for UC and CD patients. The duration and activity of the disease have the greatest impact on the QL.
Alcala MJ, Casellas F, Fontanet G, et al. Shortened questionnaire on quality of life for inflammatory bowel disease. Inflamm Bowel Dis. 2004;10:383-391
Berndtsson I, Oresland T. Quality of life before and after proctocolectomy and IPAA in patients with ulcerative proctocolitis - a prospective study. Colorectal Dis. 2003;5:173-179
Bernklev T, Jahnsen J, Lygren I, et al. Health-related quality of life in patients with inflammatory bowel disease measured with the short form-36: psychometric assessments and a comparison with general population norms. Inflamm Bowel Dis. 2005;11:909-918
Bernklev T, Jahnsen J, Henriksen M, et al. Relationship between sick leave, unemployment, disability, and healthrelated quality of life in patients with inflammatory bowel disease. Inflamm Bowel Dis 2006;12:402-12
Casellas F, Alcala MJ, Prieto L, et al. Assessment of the influence of disease activity on the quality of life of patients with inflammatory bowel disease using a short questionnaire. Am J Gastroenterol. 2004;99:457-461
D`Haenes G, Sandborn WJ, Feagan BG, Geboes K, Hanauer SB, Irvine EJ, Lemann M, Marteau P, Rutgeerts P, Scholmerich J, et.al: A review of activity indices and efficacy and points for clinical trials on medical therapy in adults with ulcerative colitis. Gastroenterology 2007;132:763-786
De Boer AG., Wijler W, Bartelsman JFW, de Haes HC: Inflammatory bowel disease questionnaire: cross-cultural adaptation and further validation. Eur J Gastroenterol Hepatol. 1995,
:1043-1050
Guyatt G, Mitchell A, Irvine EJ, et al. A new measure of health status for clinical trials in inflammatory bowel disease. Gastroenterology. 1989;96:804-810
Han SW, McColl E, Steen N., Barton JR, Welfare MR. The inflammatory bowel disease questionnaire: a valid and reliable measure in ulcerative colitis patients in the north east of England. Scand J Gastroenterol 1998, 33:961-966
Hashimoto H, Green J, Iwao Y, et al. Reliability, validity, and responsiveness of the Japanese version of the Inflammatory Bowel Disease Questionnaire. J Gastroenterol 2003;38:1138-43
Hlavaty T, Persoons P, Vermeire S, et al. Evaluation of short-term responsiveness and cutoff values of inflammatory bowel disease questionnaire in Crohn`s disease. Inflamm Bowel Dis 2006;12:199-204
Kalafateli M., Triantos Ch., Theocharis G., Giannakopoulou D., Koutroumpakis E., Chronis A., Sapountzis A., Margaritis V., Thomopoulos K., Nikolopoulou V. Health-related quality of life in patients with inflammatory bowel disease: a single-center experience. Annals of Gastroenterology (2013) 26, 243-248
Pallis AG., Vlachonikolis IG., Mouzas IA. Assessing health-related quality of life in patients with inflammatory bowel disease, in Crete, Greece. BMC Gastroenterology 2002, 2, 1-8
Reichrath J, Bens G, Bonowitz A, Tilgen W. Treatment recommendations for pyoderma gangrenosum: an evidence-based review of the literature based on more than 350 patients. J Am Acad Dermatol. 2005;53:273-83
Reinisch W, Sandborn WJ, Hommes DW, et al.Adalimumab for induction of clinical remission in moderately to severely active ulcerative colitis: results of a randomised controlled trial.Gut. 2011 Jun;60(6):780-7
Verissimo R. Quality of life in inflammatory bowel disease: psychometric evaluation of an IBDQ cross-culturally adapted version. J Gastrointest Liver Dis 2008;17:439-44
Villeneuve E, St-Pierre A, Haraoui B. Interstitial pneumonitis associated with infliximab therapy. J Rheumatol 2006; 33:1189-1193
Zahn A, Hinz U, Karner M, et al. Health-related quality of life correlates with clinical and endoscopic activity indexes but not with demographic features in patients with ulcerative colitis. Inflamm Bowel Dis 2006;12:1058-67
