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Izvestia Journal of the Union of Scientists - Varna. Medicine and Ecology Series

An approach to inflammatory corneal diseases—the role of contemporary methods

Yordan Andreev, Evgeni Neshkinski

Abstract

Aim: The aim of this article is to evaluate the opportunities for early diagnosis and treatment of inflammatory diseases of the cornea by means of contemporary methods.

Materials and Methods: A total of 32 patients with unilateral inflammatory diseases of the cornea of various etiology have been included in the study. A comprehensive ophthalmological examination with complimentary tests—an in vivo confocal microscopic and OCT of the interior segment—has been conducted.

Results: The preliminary diagnosis was revised in 14 out of 32 cases. The most common reason thereof has been an etiological inaccuracy in the initial diagnosis: bacterial, viral or fungal keratitis. The second most common reason outlined was the omission of a simultaneous illness—corneal dystrophy.   

Conclusion: The implementation of a modern algorithm of actions for corneal inflammatory diseases would facilitate faster diagnostics and improved treatment success. The correct approach to these diseases through a structured algorithm based on contemporary methods of diagnosis, treatment, and follow-up would produce a solid base for solving the existing issues.


Keywords

cornea, inflammatory disease, algorithm

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References

Whitcher, J. P., Srinivasan, M. & Upadhyay, M. P. Corneal blindness: A global perspective. Bull. World Health Organ. (2001) doi:10.1590/S0042-96862001000300009.

Schwartz, E. C. et al. Blindness and visual impairment in a region endemic for onchocerciasis in the Central African Republic. Br. J. Ophthalmol. (1997) doi:10.1136/bjo.81.6.443.

Mantopoulos, D., Cruzat, A. & Hamrah, P. In vivo imaging of corneal inflammation: New tools for clinical practice and research. Seminars in Ophthalmology (2010) doi:10.3109/08820538.2010.518542.

Austin, A., Lietman, T. & Rose-Nussbaumer, J. Update on the Management of Infectious Keratitis. Ophthalmology (2017) doi:10.1016/j.ophtha.2017.05.012.

Nielsen, E. et al. Fungal keratitis-improving diagnostics by confocal microscopy. Case Rep. Ophthalmol. (2013) doi:10.1159/000357558.

Marinova, T., Manolova, Y. & Grupcheva, C. Sjogren`s syndrome and ocular surface changes by laser-scanning in vivo confocal microscopy. Scr. Sci. Medica (2014) doi:10.14748/ssm.v46i4.1015.

Hixson, A., Blanc, S. & Sowka, J. Monitoring keratitis resolution with optical coherence tomography. Optom. Vis. Sci. (2014) doi:10.1097/OPX.0000000000000189.

Lim, S. H. Clinical applications of anterior segment optical coherence tomography. Journal of Ophthalmology (2015) doi:10.1155/2015/605729.

Soliman, W., Fathalla, A. M., El-Sebaity, D. M. & Al-Hussaini, A. K. Spectral domain anterior segment optical coherence tomography in microbial keratitis. Graefe’s Arch. Clin. Exp. Ophthalmol. (2013) doi:10.1007/s00417-012-2086-5.

Aguilar-Pérez, M. A. et al. Corneal morphological patterns detected by spectral domain optical coherence tomography in patients with infectious keratitis. Rev. Mex. Oftalmol. (2019) doi:10.24875/RMO.M18000061.

Blanchard, A., Barr, E. M. & Gilger, B. C. Evaluation of equine corneal disease using spectral domain optical coherence tomography (SD-OCT). Vet. Ophthalmol. (2019) doi:10.1111/vop.12652.




DOI: http://dx.doi.org/10.14748/isuvsme.v26i1.8110

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