Introduction: Laryngeal carcinoma is the eleventh of the most common malignant neoplasms found in men. Epidemiologically it represents 1.6-2% of all malignant tumors in males and 0.2-0.4% in females.
The Aim of the study is to characterize the incidence and significance of laryngeal carcinoma in the population.
Materials and methods: Retrospective analysis of patient records. Analysis of the following parameters has been made: age, sex, risk factors, type and frequency of accompanying diseases, ASA. Patients are divided into two groups according to the type of the surgical intervention: 1. Patients undergoing fronto-lateral resection, 2. Patients undergoing total laryngectomy.
Results: In both groups most the age of most patients is 51 to 60 years, the male sex is dominant, most of the patients are assessed with ASA III. Systemic alcohol use was reported by 195 patients who underwent fronto-lateral resection and by 520 patients who underwent total laryngectomy. Smoking was reported by 335 patients who underwent fronto-lateral resection and 840 of those who underwent total laryngectomy.
Discussion: Based on the demographic analysis, the distribution of patients by sex and age correlates with the results reported by Boring 2 and Muir 3. The predominance of patients in working-age (51-60 years) determines the social significance of the problem. A high percentage of risk factors were found in the study.
Conclusion: Laryngeal carcinoma is malignancy with high occurrence and social significance, affecting mostly males in active working-age.
American Cancer Society. Cancer facts and figures. 2007. American Cancer Society; 2007. Available at: http://www.cancer.org/docroot/STT/stt_0_2007.asp?sitearea=STT&level=1.
Boring CC, Squires TS, Tong T, Montgomery S. Cancer statistics, 1994. CA: a cancer journal for clinicians 1994; 44:7-26.
Muir C, Weiland L. Upper aerodigestive tract cancers. Cancer 1995; 75:147-153.
Siegel, Rebecca; Naishadham, Deepa; Jemal, Ahmedin. Cancer statistics, 2013. CA: a cancer journal for clinicians, 2013, 63.1: 11-30.
Siegel, Rebecca, et al. Cancer statistics, 2014. CA: a cancer journal for clinicians, 2014, 64.1: 9-29.
Tanadech Dechaphunkul MD*. Epidemiology, Risk Factors, and Overall Survival Rate of Laryngeal Cancer in Songklanagarind Hospital. J Med Assoc Thai 2011; 94 (3): 355-60.
Coleman MP, Estиve J, Damiecki P, Arslan A, Renard H. Trends in cancer incidence and mortality. IARC SciPubl 1993; (121): 1-806.
Jensen OM, Parkin DM, Lennan R, Muir CS, Skeet RG. Cancer registration. Principles and Methods. Lyon (France): International Agency for Research on Cancer; 1991.
Filho VW. The epidemiology of laryngeal cancer in Brazil. Sao Paulo Med J 2004; 122(5): 188-94.
Živković, Vladimir, et al. Epidemiological Characteristics Of Laryngeal Cancer In The Population Of The Nišava District. Acta Medica Medianae, 2014, 53.4.
Sadri M, McMahon J, Parker A. Laryngeal dysplasia: aetiology and molecular biology. The Journal of laryngology and otology 2006; 120:170-177.
Talamini R, Bosetti C, La Vecchia C et al. Combined effect of tobacco and alcohol on laryngeal cancer risk: a case-control study. Cancer causes & control : CCC 2002; 13:957-964.
Tuyns AJ, Esteve J, Raymond L et al. Cancer of the larynx/hypopharynx, tobacco and alcohol: IARC international case-control study in Turin and Varese (Italy), Zaragoza and Navarra (Spain), Geneva (Switzerland) and Calvados (France). International journal of cancer. Journal international du cancer 1988; 41:483-491.
