Инфекцията с човешкия папиломен вирус (human papilloma virus, HPV) играе важна роля в етиопатогенезата на някои злокачествени и доброкачествени заболявания както на половите органи, така и на устната кухина и фаринкса. В настоящия обзор се представят основните епидемиологични аспекти на тази инфекция, отразени в подбрани чуждестранни публикации през последните години. Имат се предвид няклои характеристики на съчетаната орална и орофарингеална и на съчетаната орална и генитална инфекция с HPV. Обръща се внимание на епидемиологическите особености на предизвиканите от HPV плоскоклетъчен рак на главата и шията и орофарингеален рак.
Human papilloma virus (HPV) infection plays a crucial role in the etiopathogenesis of certain malignant and benign diseases not only of the genital tract but also of the oral cavity and pharynx. In the present survey, the basic epidemiological aspects of this infection reflected in selected foreign publications during the recent years were presented. Some characteristics of the combined oral and oropharyngeal as well as of the combined oral and genital HPV-infection were considered. Attention was paid to epidemiological peculiarities of the squamous-cell head and neck cancer and of the oropharyngeal cancer caused by HPV.
Auluck, A., G. Hislop, C. Bajdik, C. Poh, L. Zhang, M. Rosin. Trends in oropharyngeal and oral cavity cancer incidence of human papillomavirus (HPV)-related and HPV-unrelated sites in a multicultural population: the British Columbia experience.- Cancer, 116, 2010, No 11, 2635-2644.
Chaturvedi, A. K. Epidemiology and clinical aspects of HPV in head and neck cancers.- Head Neck Pathol., 6, 2012, Suppl. 1, S16-S24.
Chauhan, S. C., M. Jaggi, M. C. Bell, M. Verma, D. Kumar. Epidemiology of human papilloma virus (HPV) in cervical mucosa.-Methods Mol. Biol., 471, 2009, 439-456.
D’Souza, G., Y. Agrawal, J. Halpern, S. Bodison, M. L. Gillison. Oral sexual behaviors associated with prevalent oral human papillomavirus infection.- J. Infect. Dis., 199, 2009, No 9, 1263-1269.
D’Souza, G., A. Dempsey. The role of HPV in head and neck cancer and review of the HPV vaccine.- Prev. Med., 53, 2011, Suppl. 1, S5-S11.
Durzyńska, J., J. Pacholska-Bogalska, M. Kaczmarek, T. Hanć, M. Durda, M. Skrzypczak, et al. HPV genotypes in the oral cavity/oropharynx of children and adolescents: cross-sectional survey in Poland.- Eur. J. Pediatr., 170, 2011, No 6, 757-761.
Edelstein, Z. R., S. M. Schwartz, S. Hawes, J. P. Hughes, Q. Feng, M. E. Stern, et al. Rates and determinants of oral human papillomavirus infection in young men.- Sex. Transm. Dis., 39, 2012, No 11, 860-867.
Gillison, M. L., X. Castellsagué, A. Chaturvedi, M. T. Goodman, P. Snijders, M. Tommasino, et al. Comparative epidemiology of HPV infection and associated cancers of the head and neck and cervix.- Int. J. Cancer, 2013 Apr 9. doi: 10.1002/ijc.28201.
Huang, S. F., H. F. Li, C. T. Liao, H. M. Wang, I. H. Chen, J. T. Chang, et al. Association of HPV infections with second primary tumors in early-staged oral cavity cancer.- Oral Dis., 18, 2012, No 8, 809-815.
Isayeva, T., Y. Li, D. Maswahu, M. Brandwein-Gensler. Human papillomavirus in non-oropharyngeal head and neck cancers: a systematic literature review.- Head Neck Pathol., 6, 2012, Suppl. 1, S104-S120.
Joseph, A. W., G. D’Souza. Epidemiology of human papillomavirus-related head and neck cancer.- Otolaryngol. Clin. North Am., 45, 2012, No 4, 739-764.
Kreimer, A. R., R. K. Bhatia, A. L. Messeguer, P. González, R. Herrero, A. R. Giuliano. Oral human papillomavirus in healthy individuals: a systematic review of the literature.- Sex. Transm. Dis., 37, 2010, No 6, 386-391.
Kreimer, A. R., A. Villa, A. G. Nyitray, M. Abrahamsen, M. Papenfuss, D. Smith, et al. The epidemiology of oral HPV infection among a multinational sample of healthy men.- Cancer Epidemiol. Biomarkers Prev., 20, 2011, No 1, 172-182.
Kumaraswamy, K. L., M. Vidhya. Human papilloma virus and oral infections: an update.- J. Cancer Res. Ther., 7, 2011, No 2, 120-127.
Lambert, R., C. Sauvaget, M. de Camargo Cancela, R. Sankaranarayanan. Epidemiology of cancer from the oral cavity and oropharynx.- Eur. J. Gastroenterol. Hepatol., 23, 2011, No 8, 633-641.
Lee, S. Y., N. H. Cho, E. C. Choi, S. J. Baek, W. S. Kim, D. H. Shin, et al. Relevance of human papilloma virus (HPV) infection to carcinogenesis of oral tongue cancer.- Int. J. Oral Maxillofac. Surg., 39, 2010, No 7, 678-683.
Machado, J., P. P. Reis, T. Zhang, C. Simpson, W. Xu, B. Perez-Ordonez, et al. Low prevalence of human papillomavirus in oral cavity carcinomas.- Head Neck Oncol., 2, 2010 Mar 12, 6. doi: 10.1186/1758-3284-2-6.
Marur, S., G. D’Souza, W. H. Westra, A. A. Forastiere. HPV-associated head and neck cancer: a virus-related cancer epidemic.-Lancet Oncol., 11, 2010, No 8, 781-789.
Parisi, S. G., M. Cruciani, R. Scaggiante, C. Boldrin, S. Andreis, F. Dal Bello, et al. Anal and oral human papillomavirus (HPV) infection in HIV-infected subjects in northern Italy: a longitudinal cohort study among men who have sex with men.- BMC Infect. Dis., 11, 2011 May 25, 150. doi: 10.1186/1471-2334-11-150.
Sanders, A. E., G. D. Slade, L. L. Patton. National prevalence of oral HPV infection and related risk factors in the U.S. adult population.- Oral Dis., 18, 2012, No 5, 430-441.
Smith, E. M., L. M. Rubenstein, T. H. Haugen, E. Hamsikova, L. P. Turek. Tobacco and alcohol use increases the risk of both HPVassociated and HPV-independent head and neck cancers.- Cancer Causes Control, 21, 2010, No 9, 1369-1378.
Syrjänen, S. Current concepts on human papillomavirus infections in children.- APMIS, 118, 2010, No 6-7, 494-509.
Termine, N., L. Giovannelli, D. Matranga, A. Perino, V. Panzarella, P. Ammatuna, et al. Low rate of oral human papillomavirus (HPV) infection in women screened for cervical HPV infection in Southern Italy: A cross-sectional study of 140 immunocompetent subjects.- J. Med. Virol., 81, 2009, No 8, 1438-1443.
Termine, N., L. Giovannelli, D. Matranga, M. P. Caleca, C. Bellavia, A. Perino, et al. Oral human papillomavirus infection in women with cervical HPV infection: new data from an Italian cohort and a metanalysis of the literature.- Oral Oncol., 47, 2011, No 4, 244-250.
Trottier, H., A. N. Burchell. Epidemiology of mucosal human papillomavirus infection and associated diseases.- Public Health Genomics, 12, 2009, No 5-6, 291-307.
Wierzbicka, M., A. Józefiak, J. Szydłowski, A. Marszałek, C. Stankiewicz, E. Hassman-Poznańska, et al. Recommendations for the diagnosis of human papilloma virus (HPV) high and low risk in the prevention and treatment of diseases of the oral cavity, pharynx and larynx. Guide of experts PTORL and KIDL.- Otolaryngol. Pol., 67, 2013, No 3, 113-134.
