В досега откритите над 200 типа HPV при 60 от тях се наблюдава склонност към малигнизация. Целта на нашето проучване, провеждащо се съвместно в катедра по Патоанатомия и УНГ-клиника при УМБАЛ „Царица Йоанна – ИСУЛ“ е намиране на хистологични критерии за стадиране на промените в епитела и адаптирането им към клиничната практика. Наблюдението се базира на степента на ангажиране сквамозния епител от коилоцитите. Те са диспластични сквамозни клетки, намиращи се в потенциално преканцерозни лезии в дихателния и проксималната част на храносмилателния тракт. Ние проследяваме зависимостта между тези съотношения и провежданата терапия.
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In detecting up to the moment more than 200 types doublestranded DNA HPV, by 60 types are observed inclination to malignant transformation. The aim of our investigation hold by Chair of pathology and ENT clinic MHAT „ TSARITZA JOANNA“ –Sofia is to find histological criteria to stadiing the changes in the epithelium from koilocytes. They are displastic squamous cells which are find in potential precancerous lesions in respiratory and proximal part of the digestive tract. We follow the dependence between these correlations and the medical treatment.
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