The Recurrent Respiratory Papillomatosis (RRP) is a relatively rare pathologic entity, which is characterized morphologically by the presence of mucous papillomatous lesions in the respiratory airways. The most frequent target organ is larynx. The RRP affects both adult and pediatric population, and the patient’s age determines some specific clinical features. Male adult patients are affected more frequently than female patients and the papillomatous lesions are solitary, and are less prone to recidivism. In the pediatric group both sexes are affected equally, the papillomatous lesions are multiple and are characterized by high recurrent rate. The article considers some epidemiologic features of pediatric RRP.
-----------------------------------
Рецидивиращата респираторна папиломатоза ( РРП ) е относително рядко заболяване, което се характеризира с разрастване на папиломи по лигавицата на дихателните пътища. Най-често засегнат е ларинксът. Заболяването засяга както деца, така и възрастни, като възрастта на поява има значение за някои особености в клиничното му протичане. При възрастните пациенти мъжете боледуват по-често от жените, папиломите най-често са единични и проявяват по-слаба склонност към рецидиви. При децата еднакво засегнати са и двата пола, папиломите са множествени и проявяват голяма склонност към рецидиви. В настоящата статия се разглеждат някои епидемиологични особености на РРП в детската възраст.
Silverman DA, Pitman MJ. Current diagnostic and management trends for recurrent respiratory papillomatosis. Curr Opin Otolaryngol Head Neck Surg
; 12: 532-7.
Armstrong LR, Derkay CS, Reeves WC. Initial results from the National Registry for Juvenile-onset recurrent papillomatosis Arch otolaryngol Head Neck Surg 1999; 125: 743-48.
Rimell FL, Shoemaker DL, Pou AM, Jordan JA, Post JC, Ehrlich GD. Pediatric respiratory papillomatosis: prognostic role of viral typing and cofactors. Laryngoscope 1997; 107: 915-18.
Derkay CS. Task force on recurrent respiratory papillomatosis. A preliminary report. Arch Otolaryngol Head Neck Surg 1995; 121: 1386 – 91.
Lindeberg H, Elbrand O. Laryngeal papillomas: the epidemiology in a Danish subpopulation 1965-1984. Clin Otolaryngol Allied Sci 1990; 15: 125-31.
Bomholt A. Juvenile laryngeal papillomatosis. An epidemiological study from the Copenhagen region. Acta Otolaryngol 1988; 105: 367-71.
Lopez AM, Castro LI, Lozano RA, Caballero TL. Epidemiology of otorhinolaryngological squamous cell papillomas in a Spanish subpopulation during a 20 year period. Rev Laryngol Otol Rhinol (Bord.) 1996; 117: 105-10.
Derkay CS, Unger B, Rimmel F. National registry for juvenile-onset recurrent respiratory papillomatosis. Centers for Disease Control and Prevention and the RRP Task Force, 2002
Bishai D, Kashima H, Shah K. The cost of juvenile-onset recurrent respiratory papillomatosis. Arch Otolaryngol Head Neck Surg 2000; 126: 935-9.
Lindman JP, Lewis LS, Accort N, Wiatrk BJ. Use of the pediatric quality of life inventory to assess the health-related quality of life in children with recurrent respiratory papillomatosis. Ann Otol Rhinol Laryngol 2005; 114: 499-503.
