Fast and proper regulated water transport across cell membranes is important for the normal function of organs. Water channels, called aquaporins (AQPs), are involved in this process. AQPs play a role in the mucus and saliva secretion. They are also involved in maintaining inner ear fluid homeostasis. The discovery of AQPs gives new opportunities for the pharmacological treatment of rhinitis, bronchitis, mucoviscidosis, sialoadenitis and Sjögren’s syndrome.
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Бързият и регулиран транспорт на водата през клетъчната мембрана е от изключителна важност за нормалното функциониране на органите. Той се осъществява от специализирани водни канали, наречени аквапорини (AQP). Аквапорините имат важно участие в секретирането на слуз и на слюнка. Те са ангажирани и в поддържане постоянството на състава и обема на системата от течности във вътрешното ухо. Откритието на аквапорините отваря възможности за разработване на нови терапевтични подходи при заболявания като ринит, бронхит, муковисцидоза, сиалоаденит и синдром на Sjögren.
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