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International Bulletin of Otorhinolaryngology

Ototoxicity in some Cancer Patients

K. Tenev, M. Hristova


To review the outcome in cancer patients who was treated with Cisplatin and other ototoxicity drugs in 6 mounts period in Oncology Department, KOC Stara Zagora.
This study suggests that there is a correlation between increase of the Sensoneural hearing loss and combination of Cisplatin and other groups of drugs by some treatment cancer patients.


Sensoneural hearing loss, vertigo, tinnitus

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A.Ecborn, A. Anderson, H.Ehrsson et al. Cisplatin-induced hearing loss: influence of the mode of drug administration in the guinea pig. Hearing Research. 2000;140:38–44

Brock et al., 2012: McWhinney et al., 2009, Shen et al., 2012: Yao et al., 2007

S. Prinja, G. Singh, M. Vashisth, T. Arora . Protective role of Calcium Channel Blocker Flunarizine on Cisplatin Induced Ototoxity: A clinical Study. Int . Journal of Contemporary Medical Research 2016; vol.3



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