Abstract
In this review is introduced literature data about fixed structural, neorochemical and functional asymmetry in schizophrenic patients. Anatomical differences in brain left temporal lobe, hippocampus, amygdala and corpus callosum are pointed as well as in thalamus and nuclei thalamici. Differences in dopamine system, glutamate receptors, level of N-acetylaspartat, some brain neoropeptides and their peptidases are present. In functional aspect the accent is on left temporal and prefrontal areas in schizophrenics.