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Scripta Scientifica Medica


D. Kostov, V. Alexandrov, N. Dragnev, N. Nikolov, N. Mankov, E. Nikolaev, R. Janeva, Hr. Mihajlov, N. Mitev, R. Asenov, Al. Filipov, G. Kobakov, V. Keranov


Aim: We present our experience with a hepatopancreatoduodenectomy as a method of surgical treatment of lateral advanced malignant tumors of the gallbladder and analyze the clinical significance of this operating procedure.Materials and Methods: The study is retrospective (2005-2014) and includes four patients with locally advanced carcinoma of the gallbladder, engaging a hepaticocholedochus, the head of the pancreas and the duodenum with a spread to the retropancreatic lymph nodes, where a hepatopancreatoduodenectomy is performed.Results: Hemihepatectomy was performed in two of the patients, while the other two had liver resections, which involved a removal of two liver segments and part of Sg1. The postoperative mortality was 0%. Postoperative complications of grade I-II according classification of Dindo-Clavien were registred in two patients. The average survival was 13 months.Conclusions: Hepatopancreatoduodenectomy is a technical challenge and may be carried out with a low incidence of postoperative complications and zero mortality. This type of surgery is the only alternative for locally advanced carcinoma of the gallbladder and the extrahepatic bile duct.


Keywords: carcinoma of the gallbladder, hepatopancreatoduodenectomy, survival

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About The Authors

D. Kostov

V. Alexandrov

N. Dragnev

N. Nikolov

N. Mankov

E. Nikolaev

R. Janeva

Hr. Mihajlov

N. Mitev

R. Asenov

Al. Filipov

G. Kobakov

V. Keranov

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