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A woman with purple toes after intrarticular hyaluronic acid administration

Valentina Broshtilova, Dimitar Nikolov, Filka Georgieva, Sonya Marina


Intra-articular injected hyaluronic acid provides pain relief and functional improvements in patients with gonarthrosis. We present a 92-year-old woman with iatrogenic blue toe syndrome after intra-articular in­jection of hyaluronic acid. This is an anecdotally rare complication, which aims to heighten the clinician`s awareness on the possible intervention pitfalls and spectrum of therapeutic indications.


hyaluronic acid, blue toe syndrome

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About The Authors

Valentina Broshtilova
Department of Dermatology and Venereolgoy, Faculty of Medicine, Medical University Sofia, Sofia, Bulgaria

Dimitar Nikolov
Department of Vascular surgery, Tokuda Hospital Sofia, Sofia, Bulgaria

Filka Georgieva
Department of infectious diseases, parasitology and dermato-venereology, Medical University, Varna, Bulgaria

Sonya Marina
Department of infectious diseases, parasitology and dermato-venereology, Medical University, Varna, Bulgaria

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