The study covered 34 workers from a manganese mine (group one) and 33 workers from a flux manufacture (group two). The following parameters were examined: total protein, protein fractions, immunoglobulins A, M, and G, total cholesterol, the enzyme activity of ASAT, ALAT, GLDH, LDH, and CE in the serum, as well as manganese in the blood by using the method of atomic absorption spectrophotometry. Blood manganese concentration was reliably elevated. There was reduction of total protein and albumin contents while alpha 2-globulins were enhanced for the second group only. The immunoglobulin A was increased which was more outlined for the group two whilst the total cholesterol increase was more manifested for the group one. All the enzymes were significantly activated. The necessity for dynamic follow-up of the parameters examined during the evaluation of the health risk and monitoring the health status of workers from manganese-dangerous projects was emphasized.
Еpшов, Ю. А., Т. В. Плетневa. Механизмы токсического действия неорганических соединений. Москва, Медицина, 1989, с. 114.
Запрянов, 3. В: Отравяния с тежки метали. Под ред. В. Бояджиев и Ц. Алексиева. София, Медицина и физкултура, 1990, с. 102.
Королев, A. А., О. А. Моденова. Гиг. и санит., 1991, № 12, 15-17.
Николова, П., Л. Халачева, Б. Кавалджиева, С. Солакова, Л. Тонева. Проучване действието на мангана върху организма на работниците от производството на флюси с оглед разработване на профилактични и оздравителни мероприятия. Варна, 1986.
Попов, Т. В: Хигиенна токсикология. Под ред. Ф. Калоянова. София, Медицина и физкултура, 1985, 96-108.
Талакин, Ю. Н., В. Г. Кирилова, М. В. Савченко. Гиг. труда и проф. забол., 1990, № 11, 18-20.
Талакин, Ю. Н., Л. А. Иванова, М. П. Байдамин, М. В. Савченко, О. А. Матвеенко, B. Н. Комиссаров, И. В. Беляева. Гиг. труда и проф. забол., 1990, № 12, 26-30.
Талакин, Ю. Н., М. В. Савченко, Л. А. Иванова. Гиг. и санит., 1992, № 2, 38-41.
Xалачева, Л., В. Бояджиев. В: I. Науч. сес. друж. хим. с мед. профил. Варна, 1975 г. Доклади. Варна, 1975, 95-100.
Amr, M. M., M. El-Batanouni, E. A. El-Dessoukey. Environ. Internat. Conf. Athens, Sept. 1985. Edinburgh, 1985, Vol. 2, p. 185.
Anсa, Z., S. Gabоr, А. Оssian. Igiena, 35, 1986, № 4, 255-260.
Веnско, В., М. Cikrt. J. Hyg. Epidemiol. Microbiol. Immunol, 28, 1984, № 2, 149-160.
Сеmpеl, M. Med. pracy, 1979, № 2, 186-189.
Сiкrt, M., P. Lеpsi, E. Lukas. J. Hyg. Epidemiol. Microbiol. Immunol., 31, 1987, № 1, 33-39.
Gotto, A. M. Lipid Rev., 1, 1987, № 1, 1-5.
Jenkins, K. J., J. K. Kramer. J. Diet. ScL, 74, 1991, № 11, 3944-3948.
Jоndеrко, G., D. Czekanska, Z. Twardowski, E. Tyrna. Med. pracy, 24, 1973, № 6, 589-600.
Klandewal, S., S. K. Tandon. Environ. Res., 24, 1981, 75-81, 82-88.
Lawrеnсе, D. Toxicol Appl. Pharmacol, 57, 1981, № 3, 439-451.
Misiеwiсz, A. Med. pracy, 3, 1983, № 2, 101-106.
Murphу, V. A., J. M. Rosenberg, Q. R. Smith, S. I. Rapoport. Neurotoxicology, 12, 1991, № 2, 253-263.
Roels, H., R. Lauwегуs, P. Gеnеt. Amer. J. Ind. Med., 11, 1987, № 3, 297-305.
Ulriсh, L., J. Mоraviс, P. Miskowiс. Pracovni lek., 41, 1990, №4, 147-151.
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