Nowadays anaemia affects a great part of the population worldwide. This problem is particularly significant because of its medical, social and economic aspects. The aim of this study was to establish the changes in myocardial perfusion after treatment with preductal in patients with chronic anaemia. The study covered 45 female patients at a mean age of 39.95±4.25 years. Echocardiographic and single-photon emission computer tomographic examinations were performed. Left ventricular size and volume and cardiac output were increased but ejection fractions and fractions of shortening were decreased prior to preductal treatment. Scintigraphy revealed an increase of the left ventricular size and thinning of the myocardium in 26.66% of the cases. There were hypo perfusion areas in 62.22% of the cases. After a 3-month preductal treatment, any changes were completely reversed and any echocardiographic parameters normalized. Hyper dynamic heart regimen increased left ventricular volume and myocardial hypo perfusion under the conditions of chronic anaemic hypoxia in patients with severe anaemia of different types. Three-month-long preductal treatment caused a complete recovery of myocardial alterations.
Scripta Scientifica Medica 2012; 44(2): 69-72.
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