The results are reported of investigations on the glucose-6-phosphate dehydrogenase deficiency in the erythrocytes of 71 individuals, descending from ten progenies of various communities (10) in the Varna district, with favism illness being established in the past history of some of them. The G-6-Ph dehydrogenase deficiency in the erythrocytes is more frequently met with in females - 71.8% of the total number of investigated women. In the male sex the enzyme deficiency is established in 43.5% of the subjects reviewed. Insofar clinical manifestation of the deficiency is concerned, the ratios are inversed. The morbidity rate in males is higher - 58.8% affected against 17.3% for females. The affected with fa\ism in the district of Varna are mainly children, younger than 10 years, whereas, among the adults merely sporadic cases are established of clinically manifested hemolysis. A number of problems, having a bearing on the pathologic gene and X-chromosome carriage are also discussed.
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