Thirty-four patients, aged between 14 and 54, who have suffered from acute viral hepatitis before 7 months to 11 years are examined. Of them in 12 (35 per cent) hypozincemia (group 1) is recorded, and in 22 (65 per cent) normozincemia (group II).
Group I includes 8 patients with chronic hepatitis with an average zincemia of 93у per cent, 3 patients with hepatitis who failed to be cured with a mean zincemia of 96y per cent and one cured with 96у per cent zinc in the serum. Group II includes 10 healthy individuals, 7 uncured cases of hepatitis and 3 with chronic hepatitis. Therefore, in 2/3 of the patients suffering from chronic hepatitis zincemia is evident. The authors observations witness that in the pathological process leading to chronification of acute viral hepatitis mechanisms which cause hypozincemia are involved. The latter is in good agreement with the results of some routine methods for deteccion of hepatic injury and represents a successful adjuvant to their
diagrwstic significance. If following acute hepatitis hypozincemia persists, this may irjdicate an eventual chronification of the ailm.ent, as well as liver insufficiency.
The autfiors have made use of the dithizone method for determination of zincemia after Wolf and modified by Rechenberger.
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