Scientific Online Resource System

Scripta Scientifica Medica

Locally advanced adenocarcinoma of the supramesocolic part of the colon . Feat ures of surgical treatment and challenges

V. Marinov, R. Gaydarski, K. Draganov, N. Katev, D. Rusenov, Y. Kolev, A. Petreska, B. Borisov, G. Chengalova, S. Lavchev, D. Penchev, D. Stoyanova, S. Tonev

Abstract

Purpose: The objective of the present study was to analyze the early results from the surgical treatment of locally advanced carcinoma of the colon in its transverse section and the two flexures.

Material and methods: The study covered 36 patients with locally advanced colonic carcinoma, 19 males and 17 females at a mean age of 65,6 years, treated in the Clinic of Liver, Biliary, Pancreatic and General Surgery, Tokuda Hospital of Sofia during the period from January 2007 to March 2013. Any necessary diagnostic and surgical methods were applied.

Results: Multivisceral resections were commonly performed in order to achieve a radical surgery in cases of locally advanced disease. Great surgeon`s experience in liver, biliary and pancreatic interventions is obligatorily required. In this paper we share our experience in the treatment of this disease for a period of 6 years.

Conclusion: Our application of the multivisceral resections results in surgical radicality along with acceptable levels of perioperative morbidity and mortality rates when compared to other studies in in the foreign literature available.


Keywords

locally advanced colonic adenocarcinoma; supramesocolic part of colon; colonic flexures; multivisceral resections; postoperative complications

Full Text


References

Amshel, C., S. Avital, A. Miller, L. Sands, F.

Marchetti, M. Hellinger. T4 rectal cancer: analysis

of patient outcome after surgical excision.- Am.

Surg., 71, 2005, No 11, 901-903, discussion 904.

Eisenberg, S. B., W. G. Kraybill, M. J. Lopez.

Long-term results of surgical resection of locally

advanced colorectal carcinoma.- Surgery, 108,

, No 4, 779-785.

Gebhardt, C., W. Meyer, S. Ruckriegel, U. Meier.

Multivisceral resection of advanced colorectal carcinoma.-

Langenbeck`s Arch. Surg., 384, 1999, No 2,

-199.

Gezen, C., M. Kement, Y. E. Altuntas, N. Okkabaz,

M. Seker, S. Vural, et al. Results after multivisceral

resections of locally advanced colorectal cancers:

an analysis on clinical and pathological T4 tumors.-

World J. Surg. Oncol., 10, 2012 Feb 15, 39.

doi: 10.1186/1477-7819-10-39.

Izbicki, J. R., S. B. Hosch, W. T. Knoefel, B. Passlick,

C. Bloechle, C. E. Broelsch. Extended resections

are beneficial for patients with locally advanced

colorectal cancer.- Dis. Colon Rectum, 38, 1995,

No 12, 1251-1256.

Kapoor, S., B. Das, S. Pal, P. Sahni, T. K. Chattopadhyay.

En bloc resection of right-sided colonic adenocarcinoma

with adjacent organ invasion.- Int. J.

Colorectal Dis., 21, 2006, No 3, 265-268.

Lehnert, T., M. Methner, A. Pollok, A. Schaible, U.

Hinz, C. Herfarth. Multivisceral resection for locally

advanced primary colon and rectal cancer. An

analysis of prognostic factors in 201 patients.- Ann.

Surg., 235, 2002, No 2, 217-225.

Lopez, M. J., V. W. Monafo. Role of extended

resection in the initial treatment of locally

advanced colorectal carcinoma.- Surgery, 113, 1993,

No 4, 365-372.

Luna-Perez, P., S. E. Rodriguez-Ramirez, M. G. De

la Barrera, M. Zeferino, S. Labastida. Multivisceral

resection for colon cancer.- J. Surg. Oncol., 80, 2002,

No 2, 100-104.

Montesani, C., G. Ribotta, R. De Milito, A. Pronio,

A. D`Amato, P. Narilli, et al. Extended resection in

the treatment of colorectal cancer.- Int. J. Colorectal

Dis., 6, 1991, No 3, 161-164.

Nakafusa, Y., T. Tanaka, M. Tanaka, Y. Kitajima,

S. Sato, K. Miyazaki. Comparison of multivisceral

resection and standard operation for locally advanced

colorectal cancer: analysis of prognostic

factors for short-term and long-term outcome.- Dis.

Colon Rectum, 47, 2004, No 12, 2055-2063.

Nelson, H., N. Petrelli, A. Carlin, J. Couture, J.

Fleshman, J. Guillem, et al.; National Cancer Institute

Expert Panel. Guidelines 2000 for colon and

rectal surgery.- J. Natl Cancer Inst., 93, 2001, No 8,

-596.

Otchy, D., N. H. Hyman, C. Simmang, T. Anthony,

W. D. Buie, P. Cataldo, et al.; Standards Practice

Task Force; American Society of Colon and Rectal

Surgeons. Practice parameters for colon cancer.-

Dis. Colon Rectum, 47, 2004, No 8, 1269-1284.

Poeze, M., J. G. Houbiers, C. J. van de Velde, T.

Wobbes, M. F. von Meyenfeldt. Radical resection of

locally advanced colorectal cancer.- Br. J. Surg., 82,

, No 10, 1386-1390.

Staib, L., K. H. Link, A. Blatz, H. G. Berger. Surgery

of colorectal cancer: surgical morbidity and fiveand

ten-year results in 2400 patients - monoinstitutional

experience.- World J. Surg., 26, 2002, No 1,

-66.

Tjandra, J. J., J. W. Kikenny, W. D. Buie, N. Hyman,

C. Simmang, T. Anthony, et al.; Standards Practice

Task Force; American Society of Colon and Rectal

Surgeons. Practice parameters for the management

of rectal cancer.- Dis. Colon Rectum, 48, 2005,

No 3, 411-423.




DOI: http://dx.doi.org/10.14748/ssm.v45i0.873
Array
Article Tools
Email this article (Login required)
About The Authors

V. Marinov
Tokuda Hospital of Sofia
Bulgaria

Clinic of Liver, Biliary, Pancreatic and General Surgery

R. Gaydarski
Tokuda Hospital of Sofia
Bulgaria

Clinic of Liver, Biliary, Pancreatic and General Surgery

K. Draganov
Tokuda Hospital of Sofia
Bulgaria

Clinic of Liver, Biliary, Pancreatic and General Surgery

N. Katev
Tokuda Hospital of Sofia
Bulgaria

Clinic of Liver, Biliary, Pancreatic and General Surgery

D. Rusenov
Tokuda Hospital of Sofia
Bulgaria

Clinic of Liver, Biliary, Pancreatic and General Surgery

Y. Kolev
Tokuda Hospital of Sofia
Bulgaria

Clinic of Liver, Biliary, Pancreatic and General Surgery

A. Petreska
Tokuda Hospital of Sofia
Bulgaria

Clinic of Liver, Biliary, Pancreatic and General Surgery

B. Borisov
Tokuda Hospital of Sofia
Bulgaria

Clinic of Liver, Biliary, Pancreatic and General Surgery

G. Chengalova
Tokuda Hospital of Sofia
Bulgaria

Clinic of Liver, Biliary, Pancreatic and General Surgery

S. Lavchev
Tokuda Hospital of Sofia
Bulgaria

Clinic of Liver, Biliary, Pancreatic and General Surgery

D. Penchev
Tokuda Hospital of Sofia
Bulgaria

Clinic of Liver, Biliary, Pancreatic and General Surgery

D. Stoyanova
Tokuda Hospital of Sofia
Bulgaria

Clinic of Liver, Biliary, Pancreatic and General Surgery

S. Tonev
Tokuda Hospital of Sofia
Bulgaria

Clinic of Liver, Biliary, Pancreatic and General Surgery

Font Size


|