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Small bowel carcinoma associated with Crohn`s disease: clinical review and case report

R. P. Gornev, M. S. Zashev, V. I. Mitova, A. T. Gegova

Abstract

Crohn`s disease is a chronic relapsing and remitting inflammation of the bowel involving all its layers. A small bowel adenocarcinoma in Crohn`s disease is a rare entity. The literature about this disease is reviewed. A case report of a 41-year male patient illustrates the significance of the diagnostic and therapeutic procedures.

Keywords

Crohn`s disease; small bowel adenocarcinoma; diagnosis; treatment; case report

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References

Abrahams, N. A., A. Halverson, V. W. Fazio, L. A.

Rybicki, J. R. Goldblum. Adenocarcinoma of the

small bowel: a study of 37 cases with emphasis on

histologic prognostic factors.- Dis. Colon Rectum,

, 2002, No 11, 1496-1502.

Adler, S. N., D. T. Lyon, P. D. Sullivan.

Adenocarcinoma of the small bowel. Clinical

features, similarity to regional enteritis, and

analysis of 338 documented cases.- Am. J.

Gastroenterol., 77, 1982, No 5, 326-330.

Bulgarian National Cancer Registry. Cancer

incidence in Bulgaria 2009. Sofia.

Feldstein, R. C., S. Sood, S. Katz. Small bowel

adenocarcinoma in Crohn`s disease.- Inflamm.

Bowel Dis., 14, 2008, No 8, 1154-1157.

Fishman, P. N., G. R. Pond, M. J. Moore, A. Oza,

R. L. Burkes, L. L. Siu, et al. Natural history

and chemotherapy effectiveness for advanced

adenocarcinoma of the small bowel: a retrospective

review of 113 cases.- Am. J. Clin. Oncol., 29, 2006,

No 3, 225-231.

Ginsburg, L., K. M. Schneider, D. H. Dreizin, C.

Levinson. Carcinoma of the jejunum occurring in

a case of regional enteritis.- Surgery, 39, 1956, No 2,

-351.

Glick, S. N. Gastric carcinoma in patients with

Crohn disease: report of four cases.- Am. J.

Roentgenol., 157, 1991, No 2, 311-314.

Kronberger, I. E., I. W. Graziadei, W. Vogel.

Small bowel adenocarcinoma in Crohn`s disease:

a case report and review of literature.- World J.

Gastroenterol., 12, 2006, No 8, 1317-1320.

Lioe, T. F., J. D. Biggart. Primary adenocarcinoma

of the jejunum and ileum: clinicopathological

review of 25 cases.- J. Clin. Pathol., 43, 1990, No 7,

-536.

Locher, C., D. Malka, V. Boige, P. Lebray, D. Elias,

P. Lasser, et al. Combination chemotherapy in

advanced small bowel adenocarcinoma.- Oncology,

, 2005, No 4, 290-294.

Polyzos, A., G. Kouraklis, A. Giannopoulos,

J. Bramis, J. K. Delladetsima, P. P. Sfikakis.

Irinotecan as salvage chemotherapy for advanced

small bowel adenocarcinoma: a series of three

patients.- J. Chemother., 15, 2003, No 5, 503-506.

Solem, C. A., W. S. Harmsen, A. R. Zinsmeister, E.

V. Loftus, Jr., et al. Small intestinal adenocarcinoma

in Crohn`s disease: a case-control study.- Inflamm.

Bowel Dis., 10, 2004, No 1, 32-35.

Sriram Bhat, M., M. Ashfaque, K. Balu,

J. Madhusudhanan, R. K. Sendhil. A rare

presentation of Crohn`s disease.- Online J. Health

Allied Sci., 6, 2007, No 4.




DOI: http://dx.doi.org/10.14748/ssm.v45i0.879
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About The Authors

R. P. Gornev
University of Sofia
Bulgaria

Department of General Surgery

M. S. Zashev
University of Sofia
Bulgaria

Department of General Surgery

V. I. Mitova
University of Sofia
Bulgaria

Department of General Surgery

A. T. Gegova
Lozenets University Hospital of Sofia, Medical Faculty, St. Kliment Ohridski University of Sofia
Bulgaria

Department of Pathology

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