Scientific Online Resource System

Scripta Scientifica Medicinae Dentalis

Change in saliva PH following intake of some homeopathic medications

Antoniya Pomakova, Nataliya Gateva, Nina Milcheva


INTRODUCTION: The role of simple carbohydrates as a major etiological factor for the carious process is well known. Studies have shown that frequent use of conventional sugar-containing medications increas­es the risk for oral health. Today, a significant proportion of the population chooses alternative medicine and particularly homeopathy for treatment and prophylaxis, considering it effective and safe. However, its influence on oral conditions and its involvement as a risk factor for oral health still remains an under-dis­cussed topic.

MATERIALS AND METHODS: The study included 18 volunteer students in dental medicine. An in vitro saliva test with colored strips was used for four consecutive weeks and after intake of three commonly used homeopathic medications. The following entries were registered: baseline value, 15th, 30th and 60th minute following the intake of the respective homeopathic doses. During the first week, the study was carried out without intake of any homeopathic medicine. The data was subjected to statistical analysis.

RESULTS: There was a fall in saliva pH following intake of homeopathic medications in all studied pa­tients. The Ñ€H reduction was most significant at the 15th minute, and the average drop for the three homeo­pathic medications was - 0.68, 0.94, 1.07, respectively. On the 30th and 60th minute, the mean pH drop re­mained the highest for the third drug.

CONCLUSION: There was a decrease in saliva pH in all individuals after administration of each medica­tion. In a significant part of the cases the drop was below the critical value of 5.5. The values remained low­er than the baseline even an hour following the intake.


homeopathy, saliva, salivary pH, homeopathic medications, dental caries

Full Text


Bhateja S, Arora G, Mahna R. Complementary & alternative therapy in dentistry: homeopathy-a review. Annals and essences of dentistry 2013;3:36-40.

Mourão LC, Moutinho H, Canabarro A. Additional benefits of homeopathy in the treatment of chronic periodontitis: a randomized clinical trial. Complement Ther Clin Pract. 2013; 19(4):246-50. doi: 10.1016/j.ctcp.2013.05.002

Smith K. Against homeopathy - a utilitarian perspective. Bioethics. 2012;26(8):398-409. doi: 10.1111/j.1467-8519.2010.01876.x

Subramaniam P, Kumar K. Change in salivary pH following use of homeopathic medicines: a preliminary study. Eur J Gen Dent. 2013;2(1):31-6. doi: 10.4103/2278-9626.106802

Witt CM, Lüdtke R, Baur R, Willich SN. Homeopathic medical practice: longterm results of a cohort study with 3981 patients. BMC Public Health. 2005;5(3):115-23. doi: 10.1186/1471-2458-5-115

Bhat SS, Sargod SS, George D. Dentistry and homeopathy: an overview. Dent Update. 2005;32(8):486-8.

Upadhyay RP, Nayak C. Homeopathy emerging as nanomedicine. Ind J Res Homoeopathy 2012;6(3):31-8.

Amoroso P, Ãvila FA, Gagliardi CM. Prevalence of different Streptococci species in the oral cavity of children and adolescents. Braz J Oral Sci. 2003;2(4):164-8. doi: 10.20396/bjos.v2i4.8641674

Ayele FA, Taye BW, Ayele TA, Gelaye KA. Predictors of dental caries among children 7-14 years old in Northwest Ethiopia: a community based crosssectional study. BMC Oral Health. 2013;13-27. doi:10.1186/1472-6831-13-7.

Ferreira-Nóbilo Nde P, Tabchoury C, Sousa Mda L, Cury JA. Knowledge of dental caries and salivary factors related to the disease: influence of the teaching-learning process. Braz Oral Res. 2015;29(1):1-7. doi: 10.1590/1807-3107BOR-2015.vol29.0061

Guo L, Hu W, He X, Lux R, McLean J, Shi W. Investigating acid production by Streptococcus mutans with a surface-displayed pH-sensitive green fluorescent protein. PLoSONE. 2013;8(2):e57182. doi:10.1371/journal.pone.0057182

Stephan RM. Changes in hydrogen-ion concentration on tooth surfaces and in carious lesions. JADA. 1940;27(5):718-23. doi: 10.14219/jada. archive.1940.0178

Xiao J, Klein MI, Falsetta ML, Lu B, Delahunty CM, Yates JR III, et al. The Exopolysaccharide Matrix Modulates the Interaction between 3D Architecture and Virulence of a Mixed-Species Oral Biofilm. PLoS Pathog 2012;8(4): e1002623. doi: 10.1371/ journal.ppat.1002623

Vroom JM, DeGrauw KJ, Gerritsen HC, Bradshaw DJ, Marsh PD, Watson GK et al. Depth penetration and detection of pH gradients in biofilms by two-photon excitation microscopy. Appl Environ Microbiol. 1999;65(8):3502-11.

The Free Library. Alternative medicine for the dental professional. 2009, American Dental Hygienists` Association 27 May. 2017. Available from: https:// +the+dental+professional.-a0193298316

Fry J, Brooks D, McColl I. NHS data Book. Lancaster: MTP Press;1984.

Feigal RJ, Gleeson MC, Beckman TM, Greenwood ME. Dental caries related to liquid medication intake in young patients. ASDC J Dent Child. 1984;51(5):360-2.

Paramesh H. Epidemiology of asthma in India. Indian J Pediatr. 2002;69(4):309 12. doi:10.1007/ BF02723216

Nankar M, Walimbe H, Bijle M, Kontham U, Kamath A, Muchandi S. Comparative evaluation of cariogenic and erosive potential of commonly prescribed pediatric liquid medicaments: An in vitro study. J Contemp Dent Pract. 2014;15(1):20-5. doi: 10.5005/jp-journals-10024-1481

Nirmala S.V.S.G., Popuri VD, Chilamakuri S, Nuvvula S, Veluru S, Babu MS. Oral health concerns with sweetened medicaments: Pediatricians` acuity. J Int Soc Prevent Community Dent. 2015; 5(1):35-9. doi: 10.4103/2231-0762.151973

Pierro VS, Abdelnur JP, Maia LC, Trugo LC. Free sugar concentration and pH of paediatric medicines in Brazil. Community Dent Health. 2005;22(3):180 3.

Saeed S, Bshara N, Trak J, Mahmoud G. An in vitro analysis of the cariogenic and erosive potential of pediatric liquid analgesics. J Indian Soc Pedod Prev Dent. 2015; 33(2):143-6. doi: 10.4103/0970-4388.155129

Valinoti AC, da Silva Pierro VS, da Silva EM, Maia LC. In vitro alterations in dental enamel exposed to acids medicines. Int J Paed Dent. 2011; 21(2):141- 150. doi: 10.1111/j.1365-263X.2010.01104.x

Sahgal J, Sood PB, Raju OS. A comparison of oral hygiene status and dental caries in children on long term liquid oral medications to those not administered with such medications. J Indian Soc Pedod Prev Dent. 2002;20(4):144-151.

Rekola M. In vivo acid production from medicines in syrup form. Caries Res. 1989;23(6):412 6. doi: 10.1159/000261219

Eames S, Darby P. Homeopathy and its ethical use in dentistry. Br Dent J. 2011;210(7):299-301. doi: 10.1038/sj.bdj.2011.237

Barry C. The Body, Health and Healing in Alternative and Integrated Medicine: An Ethnography of Homeopathy in South London. Brunel University; 2003.

Hahnemann S, O`Reily WB, editor. Organon of the Medical Art. Palo Alto, California (USA): Birdcage Books; 1996.



About The Authors

Antoniya Pomakova
Medical University of Varna

Faculty of dental medicine, Pediatric dentistry department

Nataliya Gateva
Medical University - Sofia

Nina Milcheva
Medical University of Varna

Font Size