Introduction: The anatomical relations between the roots of the distal teeth and the mandibular canal (MC) are clinically important, as well as the possible complications when they are not taken into account. The three-dimensional analysis of the lower jaw is a key aspect in ensuring safe intervention in its distal sections.
Aim: The aim of this study is to investigate the relative location of the mandibular canal to the tooth apices, and the possible differences between males and females, different age groups, and between left and right half of the mandible.
Material and Methods: Cone-beam computed tomography (CBCT) scans from 100 patients were used to evaluate measurements from 600 teeth and respective MC areas.
Results: Direct contact between the root tips and the MC was found in 3.9% of the examined apices and penetration in the MC – in 0.8%. The average reported distance between the apices and the MC is shortest at the distal roots of the second molars. The values, registered for the female patients, were significantly lower than those for the male patients. No statistically significant difference was noted between the measurements in the left and the right half. Significant difference between the age groups was found only in single areas.
Conclusion: Clinicians should be aware of the proximity of the root apices to the MC before attempting surgical and root canal procedures in the posterior mandible. Direct communication between the tips of the roots and the MC is not rare and may result in serious nerve injuries if underestimated.
Ali AS, Benton JA, Yates JM. Risk of inferior alveolar nerve injury with coronectomy vs surgical extraction of mandibular third molars-A comparison of two techniques and review of the literature. J Oral Rehabil. 2018;45(3):250-7. doi: 10.1111/joor.12589.
Agbaje JO, de Casteele EV, Salem AS, Anumendem D, Lambrichts I, Politis C. Tracking of the inferior alveolar nerve: its implication in surgical planning. Clin Oral Investig. 2017;21(7):2213-20. doi: 10.1007/s00784-016-2014-x.
López-López J, Estrugo-Devesa A, Jané-Salas E, Segura-Egea JJ. Inferior alveolar nerve injury resulting from overextension of an endodontic sealer: non-surgical management using the GABA analogue pregabalin. Int Endod J. 2012;45(1):98-104. doi: 10.1111/j.1365-2591.2011.01939.x.
Pogrel MA, Dorfman D, Fallah H. The anatomic structure of the inferior alveolar neurovascular bundle in the third molar region. J Oral Maxillofac Surg. 2009;67(11):2452-4. doi: 10.1016/j.joms.2009.06.013.
Kovisto T, Ahmad M, Bowles WR. Proximity of the mandibular canal to the tooth apex. J Endod. 2011;37(3):311-5. doi: 10.1016/j.joen.2010.11.030.
Juodzbalys G, Wang HL, Sabalys G. Anatomy of mandibular vital structures. Part I: mandibular canal and inferior alveolar neurovascular bundle in relation with dental implantology. J Oral Maxillofac Res. 2010;1(1):e2. doi: 10.5037/jomr.2010.1102.
Kim ST, Hu KS, Song WC, Kang MK, Park HD, Kim HJ. Location of the mandibular canal and the topography of its neurovascular structures. J Craniofac Surg. 2009;20(3):936-9. doi: 10.1097/SCS.0b013e3181a14c79.
Haas LF, Dutra K, Porporatti AL, Mezzomo LA, De Luca Canto G, Flores-Mir C, et al. Anatomical variations of mandibular canal detected by panoramic radiography and CT: a systematic review and meta-analysis. Dentomaxillofac Radiol. 2016;45(2):20150310. doi: 10.1259/dmfr.20150310.
Shah NP, Murtadha L, Brown J. Bifurcation of the inferior dental nerve canal: an anatomical study. Br J Oral Maxillofac Surg. 2018;56(4):267-71. doi: 10.1016/j.bjoms.2018.01.016.
Pelka M, Petschelt A. Permanent mimic musculature and nerve damage caused by sodium hypochlorite: a case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008;106(3):e80-3. doi: 10.1016/j.tripleo.2008.05.003.
Wilbrand JF, Wilbrand M, Schaaf H, Howaldt HP, Malik CY, Streckbein P. Embolia cutis medicamentosa (Nicolau syndrome) after endodontic treatment: a case report. J Endod. 2011;37(6):875-7. doi: 10.1016/j.joen.2011.01.004.
Renton T, Yilmaz Z. Profiling of patients presenting with posttraumatic neuropathy of the trigeminal nerve. J Orofac Pain. 2011;25(4):333-44.
Braut V, Bornstein MM, Lauber R, Buser D. Bone dimensions in the posterior mandible: a retrospective radiographic study using cone beam computed tomography. Part 1--analysis of dentate sites. Int J Periodontics Restorative Dent. 2012;32(2):175-84.
Scarfe WC, Farman AG, Sukovic P. Clinical applications of cone-beam computed tomography in dental practice. J Can Dent Assoc. 2006;72(1):75-80.
Kamburoğlu K, Kiliç C, Ozen T, Yüksel SP. Measurements of mandibular canal region obtained by cone-beam computed tomography: a cadaveric study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009;107(2):e34-42. doi: 10.1016/j.tripleo.2008.10.012.
Arisan V, Karabuda ZC, Avsever H, Özdemir T. Conventional multi-slice computed tomography (CT) and cone-beam CT (CBCT) for computer-assisted implant placement. Part I: relationship of radiographic gray density and implant stability. Clin Implant Dent Relat Res. 2013;15(6):893-906. doi: 10.1111/j.1708-8208.2011.00436.x.
Cassetta M, Stefanelli LV, Pacifici A, Pacifici L, Barbato E. How accurate is CBCT in measuring bone density? A comparative CBCT-CT in vitro study. Clin Implant Dent Relat Res. 2014;16(4):471-8. doi: 10.1111/cid.12027.
Hillerup S. Iatrogenic injury to oral branches of the trigeminal nerve: records of 449 cases. Clin Oral Investig. 2007;11(2):133-42. doi: 10.1007/s00784-006-0089-5.
Hillerup S. Iatrogenic injury to the inferior alveolar nerve: etiology, signs and symptoms, and observations on recovery. Int J Oral Maxillofac Surg. 2008;37(8):704-9. doi: 10.1016/j.ijom.2008.04.002.
Barker S, Renton T, Ormrod S. A Qualitative Study to Assess the Impact of Iatrogenic Trigeminal Nerve Injury. J Oral Facial Pain Headache. 2019;33(2):153–9. doi: 10.11607/ofph.2054.
Abarca M, van Steenberghe D, Malevez C, De Ridder J, Jacobs R. Neurosensory disturbances after immediate loading of implants in the anterior mandible: an initial questionnaire approach followed by a psychophysical assessment. Clin Oral Investig. 2006;10(4):269-77. doi: 10.1007/s00784-006-0065-0.
Littner MM, Kaffe I, Tamse A, Dicapua P. Relationship between the apices of the lower molars and mandibular canal--a radiographic study. Oral Surg Oral Med Oral Pathol. 1986;62(5):595-602. doi: 10.1016/0030-4220(86)90326-9.
Sato I, Ueno R, Kawai T, Yosue T. Rare courses of the mandibular canal in the molar regions of the human mandible: a cadaveric study. Okajimas Folia Anat Jpn. 2005;82(3):95-101. doi: 10.2535/ofaj.82.95.
Denio D, Torabinejad M, Bakland LK. Anatomical relationship of the mandibular canal to its surrounding structures in mature mandibles. J Endod. 1992;18(4):161-5. doi: 10.1016/S0099-2399(06)81411-1.
Simonton JD, Azevedo B, Schindler WG, Hargreaves KM. Age- and gender-related differences in the position of the inferior alveolar nerve by using cone beam computed tomography. J Endod. 2009;35(7):944-9. doi: 10.1016/j.joen.2009.04.032.
Aksoy U, Aksoy S, Orhan K. A cone-beam computed tomography study of the anatomical relationships between mandibular teeth and the mandibular canal, with a review of the current literature. Microsc Res Tech. 2018;81(3):308-14. doi: 10.1002/jemt.22980.
Bürklein S, Grund C, Schäfer E. Relationship between Root Apices and the Mandibular Canal: A Cone-beam Computed Tomographic Analysis in a German Population. J Endod. 2015;41(10):1696-700. doi: 10.1016/j.joen.2015.06.016.
Kawashima Y, Sakai O, Shosho D, Kaneda T, Gohel A. Proximity of the Mandibular Canal to Teeth and Cortical Bone. J Endod. 2016;42(2):221-4. doi: 10.1016/j.joen.2015.11.009.
Alswat KA. Gender Disparities in Osteoporosis. J Clin Med Res. 2017;9(5):382-7. doi: 10.14740/jocmr2970w.