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Scripta Scientifica Pharmaceutica

Synthesis of two isomers of 3-amino-7α-12α-dihydroxy-5β-cholanic acid

Denn Barsuk, Alexandr Stremouhov, Sergiy Kovalenko

Abstract

This paper presents an optimized synthesis of two stereoisomers of 3-amino-7-12-dyhydroxycholanic acid. It was possible to obtain α-isomer in sufficient quantity. Unfortunately we could not receive β-isomer with the best yield currently.


Keywords

cholic acid; stereoisomers; 3-amino-7α-12α-dihydroxy-5β-cholanic acid

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DOI: http://dx.doi.org/10.14748/ssp.v1i2.774

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About The Authors

Denn Barsuk
National University of Pharmacy, Kharkov
Ukraine

Alexandr Stremouhov
National University of Pharmacy, Kharkov
Ukraine

Department of Pharmacognosy

Sergiy Kovalenko
National University of Pharmacy, Kharkov
Ukraine

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