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Association between blood glucose on admission and 2-hour glucose during oral glucose tolerance test in patients with acute coronary syndrome without known diabetes

Mila Boyadzhieva, Atanas Angelov, Kiril Hristozov, Svetoslav Georgiev, Darina Georgieva-Hristova, Daniela Arabadzhieva

Abstract

Introduction: Hyperglycemia during acute coronary syndrome (ACS) in patients without known diabetes is common and is considered `stress hyperglycemia`. On the other hand, it could be the first indication for previous unrecognized glycemic abnormality.

Aim: To search for correlation between blood glucose (BG) at acute admission due to ACS and glycemic parameters during oral glucose tolerance test (OGTT). Materials and methods: A standard OGTT 3-10 days after hospital discharge was applied in 96 patients without history of glucose abnormalities who underwent coronary angiography (CA) percutaneous coronary intervention (PCI). Glucose tolerance was defined according to WHO-2006 criteria for fasting plasma glucose (FPG) and 2-hour-plasma glucose (2-h-PG). The BG at acute admission in 39 ACS patients was analyzed.

Results: We found impaired glucose metabolism in 64.58% and 2-hour-hyperglycemia (≥7,8 mmol/L) in 52,1% of study participants after the OGTT. Mean BG at acute admission in subjects with newlydiagnosed type 2 diabetes mellitus (nT2DM) was 9,551,93 mmol/L. It was significantly higher com


Keywords

glucose at admission, OGTT, acute coronary syndrome, diabetes

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References

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DOI: http://dx.doi.org/10.14748/vmf.v6i1.1956

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