Scientific Online Resource System

Varna Medical Forum

Quality of life in patients with primary open-angle glaucoma depending on the conducted treatment

Yordan Yordanov, Binna Nencheva, Zarka Stoycheva


Introduction: The treatment of glaucoma can impact the quality of life (QoL) of the patients in several ways. Local and systemic side effects, difficulties in administering medications as well as the complexity of the medication therapeutic schemes are factors which can reduce the degree of patient satisfaction from the therapy.

Aim: The aim of this study is to evaluate the quality of life of patients with primary open-angle glaucoma in terms of the conducted treatment.

Materials and Methods: The study enrolled 302 patients with open-angle glaucoma. A comparative analysis of the QoL of patients with glaucoma was conducted, depending on the therapy and the side effects. The results were processed statistically using SPSS v.20 for Windows.

Results: There is a significant difference in the QoL of patients who are subjected to different treatments (F=7.08; p < 0.001). The patients where all three treatment methods - medications, laser and operation have been applied have the lowest QoL. The observed side effects are pain, irritation and itching in and around the eyes (39.70%) and difficulties in applying the eye drops (18.70%) and all of them lead to low QoL.

Conclusion: The anti-glaucoma treatment is a long-term one and often includes multiple medicinal therapies, increasing the possibility of undesired side effects with time and thus requiring a treatment plan that can stop the vision loss providing good QoL at the same time.


quality of life; treatment; primary open-angle glaucoma; side effects

Full Text


Al-Nuaimi D, Salam T, Raj S. Side effects of eye drops v compliance: patients' perspectives. Program and abstracts of the World Glaucoma Congress 2009; July 8-11, 2009; Boston, Massachusetts. Abstract P419

Donabedian A. The quality of care. How can it be assessed? JAMA. 1988;260:1743-8

Guldvog B. Can patient satisfaction improve health among patients with angina pectoris? Int J Qual Health Care. 1999;11:233-40

Jampel HD, Schwartz GF, Robin AL, et al. Patient preferences for eye drop characteristics: a willingness-to-pay analysis. Arch Ophthalmol. 2003;121:540-6

Kanski J. J. Primary Congenital Glaucoma In Clinical Ophthalmology Butterworth-Heinemann, fifth edition, 2003; 245-248

Marquis MS, Davies AR, Ware JE Jr. Patient satisfaction and change in medical care provider: a longitudinal study. Med Care. 1983;21:821-9

Nelson CJ, Weinberger MI, Balk E, et al. The chronology of distress, anxiety, and depression in older prostate cancer patients. Oncologist. 2009;14:891-9

Noeker RJ, Herrygers LA, Anwaruddin R. Corneal and conjunctival changes caused by commonly used glaucoma medications. Cornea. 2004;23:490-496



Font Size