Scientific Online Resource System

Varna Medical Forum

Uncorrected Tetralogy Of Fallot In A 60-Year-Old Female: Ethiopathogenetic Mechanisms Of The Observed Survival

Simona Nikolaeva Dimulska, Atanas Angelov Atanasov

Abstract

Tetralogy of Fallot is the most common form of cyanotic congenital heart disease in childhood but rarely seen in adulthood. The incidence is 0.26% - 0.8% out of 1000 newborns. The male sex is affected more often. It includes four components: ventricular septal defect, obstruction to the right ventricular outflow tract, overriding aorta and right ventricular hypertrophy. After the diagnosis is clear, the treatment is 100% surgical - full correction during the first two years. About 25% of the untreated children die within the first year. Only 5% of the untreated patients reach the age of 40 years and they develop right-sided heart failure. We present the case of a 60-year-old female patient with an uncor-rected tetralogy of Fallot, with discussion of the ethiopathogenetic mechanisms of the observed survival.

Keywords

tetralogy of Fallot, survival

Full Text


References

Бураковский ВИ, ЛА Бокерия. Тетрада Фалло, Сердечно-сосудистая хирургия изд. „Медицина“ Москва 1989, 167–188 .

Alonso A, C Downey , T Kuvin. Uncorrected tetralogy of Fallot in an 86-year old patient. Am J Geriart Cardiol, 2007, 16: 38-41.

Apitz CH, RH Anderson, AN Redington. Tetralogy of Fallot with pulmonary stenosis. Paediatric cardiology, third ed, New York, 2010: 753-773.

Bertranou EG , EH Blackstone, JB Hazelrig, et al. Life expectancy without surgery in tetralogy of Fallot. Am J Cardiol, 1978, 42: 458-466.

Brickner M, Hillis L, Lange R. Congenital heart disease in adults - second or two parts. N Engl J Med 2000, 342: 334-342.

Makaryus A, I Aronov, J Diamond et al. Survival to the age of 52 years in a man with unrepaired tetralogy of Fallot. Echocardiography 2004, 7: 631-637.

Marquis R. Longenity and the history of the Tetralogy of Fallot. Br Med J 1956, 1 (4971): 819-822; 826 -3 - 826-4.

Nagao G, G Daound, A McAdams. Cardiovascular anomalies associated with tetralogy of Fallot. Am J Cardiol 1967, 20: 206.

Rygg H, K Olesen, I Boesen. The life history of tetralogy of Fallot. Dan Med Bull 1971, 18: 25-30.

Valsaguacomo E, D Kellenberg. Remodeling of the right ventricle after early pulmonary valve replacement in the children with repaired tetralogy of Fallot: assessment by cardiovascular magnetic resonance. Eur Heart J 2005, 26: 2721-2721.

White D, B Sprague. Tetralogy of Fallot. Report of a case in noted musician, who lived to his 60th year. JAMA, 1929, 92787-92790.

Wren C, J O`Sullivan. Survival with congenital heart disease and need for follow up in adult life. Br J Cardiol, 2002, 9: 92-98.

Yang L, J Freeman et C Ross. Unoperated tetralogy of Fallot: case report of a natural survivor, who died in his 73rd year. Is it ever late to operate? Postgrad Med J 2005, 81: 133-134.




DOI: http://dx.doi.org/10.14748/vmf.v7i2.5581

Refbacks

User Guide

Font Size


|