Scientific Online Resource System

Bulgarian Review of Ophthalmology

Straatsma`s syndrome. Ipsilateral myelinated retinal nerve fibres, axial myopia, amblyopia syndrome

N. Veleva, A. Oscar, P. Kemilev, V. Chernodrinska

Abstract

Myelinated retinal nerve fibers (MRNF) or so called fibrae medullaris retinae are rare congenital anomaly. In most cases it is isolated ocular pathology, usually asymptomatic and diagnosed accidentally. They may present in a syndrome characterised by ipsilateral myelinated retinal nerve fibres, axial myopia and amblyopia - triad of Straatsma. We report three cases of this rare congenital condition.

Keywords

myelinated retinal nerve fibres; amblyopia; axial myopia; Straatsma`s syndrome

Full Text


References

Aaby AA, Kushner BJ. Acquired and progressive myelinated nerve fibers. Archives of ophthalmology. 1985;103:542-544.

Ali BH, Logani S, Kozlov KL, Arnold AC, Bateman B. Progression of retinal nerve fiber myelination in childhood. American Journal of Ophthalmology. 1994;118:515-517.

Chavis PS, Tabbara KF. Demyelination of retinal myelinated nerve fibers in Behcet`s disease. Documenta ophthalmologica. Advances in ophthalmology. 1998;95(2):157-64.

Elbaz H et al. Prevalence and associations of myelinated retinal nerve fibers: Results From the Population-Based Gutenberg Health Study. Retina. 2016 Jun 2.

Ellis GS, Jr, Frey T, Gouterman RZ. Myelinated nerve fibers, axial myopia, and refractoryamblyopia: An organic disease. J Pediatr Ophthalmol Strabismus. 1987;24:111-9.

FitzGibbon T, Nestorovski Z. Morphological consequences of myelination in the human retina. Exp Eye Res. 1997;65(6):809- 819.

Grzybowski A, Winiarczyk I. Myelinated retinal nerve fibers (MRNF) - Dilemmas related to their in􀃀 uence on visual function. Saudi J Ophthalmol. 2015 Jan-Mar;29(1):85-8.

Gupta A, Khandalavala B, Bansal RK,Jain IS, Grewal SP. Atrophy of myelinated nerve fibers in pituitary adenoma. Journal of clinical neuro-ophthalmology. 1990;10(2):100-2.

Jean-Louis G, Katz BJ, Digre KB, Warner JE, Creger DD. Acquired and progressive retinal nerve fiber layer myelination in an adolescent. American Journal of Ophthalmology. 2000;130(3):361-2.

Juhn AT, Houston SK 3rd, Mehta S. Bilateral Straatsma syndrome with nystagmus. Retin Cases Brief Rep. 2015 Summer;9(3):198-200.

Käsmann B, Höh H, Ruprecht KW. Results of occlusion therapy in anisomyopic amblyopia with myelinated nerve fibers. Ger J Ophthalmol. 1996 Jul;5(4):241-5.

Katz SE, Weber PA. Photographic documentation of the loss of medullated nerve fibers of the retina in uncontrolled primary open angle glaucoma. Journal of Glaucoma. 1996;5(6):406-9.

Kee C, Hwang JM.Visual prognosis of amblyopia associated with myelinated retinal nerve fibers. Am J Ophthalmol. 2005 Feb;139(2):259-65.

Kodama T, Hayasaka S, Setogawa T. Myelinated retinal nerve fibers: prevalence, location and effect on visual acuity. International Journal of Ophthalmology. 1990;200(2):77-83.

Lee MS, Gonzalez C. Unilateral peripapillary myelinated retinal nerve fibers associated with strabismus, amblyopia, and myopia. Am J Ophthalmol. 1998 Apr; 125(4):554-6.

Lee JC, Salchow DJ. Myelinated retinal nerve fibers associated with hyperopia and amblyopia. J AAPOS. 2008 Aug;12(4):418-9.

Mashayekhi A, Shields CL, Shields JA. Disappearance of retinal myelinated nerve fibers after plaque radiotherapy for choroidal melanoma. Retina 2003;23(4):572-3.

Naghib J. Triad of myelinated retinal nerve fibers, axial myopia and amblyopia. J Ophthalmic Vis Res.2010;5:284-5.

Oh BL, Hwang JM, Woo SJ. Myelinated nerve fiber-associated local scleral excavation and induced axial myopia. Retina. 2014 Oct;34(10):2028-36.

Osaguona VB, Uhumwangho OM. Syndrome of myelinated retinal nerve fibres, myopia, amblyopia and strabismus in a Nigerian. Niger Med J. 2014 Nov;55(6):517-8.

Parulekar M V, Elston JS. Acquired retinal myelination in neurofibromatosis 1. Archives of ophthalmology. 2002;120(5):659-5.

Sharpe JA, Sanders MD. Atrophy of myelinated nerve fibres in the retina in optic neuritis. The British journal of ophthalmology. 1975;59(4):229-32.

Shelton JB, Digre K, Gilman J, Warner J, Katz B. Characteristics of Myelinated Retinal Nerve Fiber Layer in Ophthalmic ImagingFindings on Auto􀃀 uorescence, Fluorescein Angiographic, Infrared, Optical Coherence Tomographic, and Red-free Images. JAMA Ophthalmol. 2013;131(1):107-109.

Shenoy R, Bialasiewicz AA, Al Barwani B. Bilateral hypermetropia, myelinated retinal nerve fibers, and amblyopia. Middle East Afr J Ophthalmol. 2011 Jan;18(1):65-6.

Straatsma BR, Foos RY, Heckenlively JR, Taylor GN. Myelinated retinal nerve fibers. American journal of ophthalmology. 1981;91(1):25-38.

Summers CG, Romig L, Lavoie JD. Unexpected good results after therapy for anisometropic amblyopia associated with unilateral peripapillary myelinated nerve fibers. J Pediatr Ophthalmol Strabismus.1991;28:134-6.

Tarabishy AB, Alexandrou TJ, Traboulsi EI Syndrome of myelinated retinal nerve fibers, myopia, and amblyopia: a review. Surv Ophthalmol. 2007 Nov-Dec; 52(6):588-96.

Teich SA. Disappearance of myelinated retinal nerve fibers after a branch retinal artery occlusion. American journal of ophthalmology. 1987;103(6):835-7

Virchow VR. Zur pathologischen anatomic der netzaut und des scherven. Virchows Arch Pathol Anat. 1856;10:170-193.

Wang Y, Gonzalez C. Unilateral myelinated nerve fibers associated with hypertropia, strabismus and amblyopia. Reverse Straatsma syndrome? Binocul Vis Strabismus Q. 2008;23:235-7.

Williams TD . Medullated retinal nerve fibers: speculations on their cause and presentation of cases. Am J Optom Physiol Opt. 1986 Feb; 63(2):142-51.

Yalcin E, Balci O, Akingol Z.Association of extensive myelinated nerve fibers and high degree myopia: case report. Indian J Ophthalmol. 2013 Oct;61(10):606-7.




DOI: http://dx.doi.org/10.14748/bro.v0i1.4523

Refbacks

Font Size


Article Tools
Email this article (Login required)
About The Authors

N. Veleva
Department of Ophthalmology - Medical University, Sofia Eye Clinic - UH `Alexandrovska`, Sofia
Bulgaria

A. Oscar
Department of Ophthalmology - Medical University, Sofia Eye Clinic - UH `Alexandrovska`, Sofia
Bulgaria

P. Kemilev
Department of Ophthalmology - Medical University, Sofia Eye Clinic - UH `Alexandrovska`, Sofia
Bulgaria

V. Chernodrinska
Department of Ophthalmology - Medical University, Sofia Eye Clinic - UH `Alexandrovska`, Sofia

|