Introduction: Retinopathy of prematurity (ROP) is a serious, vision threatening disease and among the leading causes of irreversible loss of vision. It affects prematurely born children, predominantly prior to the 32nd GW or with a body weight at birth below 1500 g. The highest risk for the development of ROP includes the time period of two weeks before to two weeks after the supposed due date. Materials and Methods: We included 10 prematurely born children with ROP requiring therapy. All of the children were screened by indirect ophthalmoscopy and the condition was documented by RetCam imaging. The treatment was conducted by the application of 810 nm diode laser. Results: Nine out of the 10 children were born before 32 GW and were with a body weight at birth below 1500 g. The disease was bilateral in 9 of the children. Laser therapy was applied to all 10 children and 18 eyes. Discussion and Conclusion: The active ophthalmological screening of all children born before 32 GW and with a body weight at birth below 1500 g, including all new-born children at risk, and the application of early laser treatment are the basis for the prevention of the development of irreversible visual loss.
Младенов О. Ретинопатия на недоносеното. Практическа педиатрия. 2017; 9: 14-16.
Оскар А, Чернодринска С, Петкова И. Клиничен случай на дете с ретинопатия на недоносеността, леку-вано с интравитреална апликация на Bevacizumab. Педиатрия. 2012; 1: 52-53.
Чернодринска В, Оскар А, Чернинкова С. RetCam скрининг на недоносени деца и оценка на рисковите за развитие на ретинопатия. Педиатрия. 2011; 4:21-23.
Adams GW, Bunce C, Xing W et al. Treatment trends for retinopathy of prematurity in the UK: active surveillance study of infants at risk. BRJ 2017; 7:3.
Bashinsky A. Retinopathy of Prematurity. N C Med J. Mar-Apr 2017; 78 (2): 124-128.
Chen Y, Li F, Deng X et al. The efficiency of 810 nm diode laser photocoagulation for type 1 retinopathy of prematurity. Chin J Ophthalmol, 2015;51(11):814-7.
Darlow B, Gilbert C. Retinopathy of Prematurity – A wold update. Semin Perinatol, 2019 Oct;43(6):315-316.
DeJonge MH, Ferrone PJ, Trese MT. Diode laser ablation for threshold retinopathy of prematurity. Short-term structural outcome. Arch Ophthalmol, 2000;118:365-367.
Dogra M, Katoch D, Dogra M. An Update on Retinopathy of Prematurity. Indian J Pediatr, 2017 Dec; 84(12):930-936.
Early Treatment of Retinopathy of Prematurity Cooperative Group. The incidence and course of retinopathy of prematurity: findings from early treatment for retinopathy of prematurity study. Pediatrics, 2005;116 (1):15-23.
ICROP Committee for Classification of Late Stages ROP, An international classification of retinopathy of prematurity, II: the classification of retinal detachment. Arch Ophthalmol, 1987;105:906- 912.
Jalali S, Azad R, Trehan H et al. Technical aspects of laser treatment for acute retinopathy of prematurity under topical anesthesia. Indian J Ophthalmol, 2010 Nov-Dec; 58 (6): 509-515.
Hartnett M. Advances in understanding and management of retinopathy of prematurity. Sure Ophthalmol, May-Jun 2017;62(3):257-276.
Lee JY, Chae JB, Yang SJ et al. Effects of intravitreal bevacizumab and laser in retinopathy of prematurity therapy on the development of peripheral retinal vessels. Graefe’s Arch Clin Exp Ophthalmol, 2010;248:1257-1262.
Nicoara SD, Cristian C, Irimescu I et al. Diode laser photocoagulation for retinopathy of prematurity: outcomes after 7 years of treatment. J Pediatr Ophthalmol Strab, 2014;51(1):39-45.
Ospina LH, Lyons CJ, Matsuba C et al. Argon laser photocoagulation for retinopathy of prematurity – long-term outcome. Eye, 2005; 19:1213-1218.
Parvaresh MM, Modarres M, Falavarjani KG et al. Transscleral diode laser retinal photocoagulation for the treatment of threshold retinopathy of prematurity. J AAPOS, 2009; 13:535-538.
Prepiakova Z, Tomcikova D, Kostolna B, Gerinec A. Confluent diode laser coagulation: the gold standard of therapy for retinopathy of prematurity. J Pediatr Ophthalmol Strab, 2015;52(1):43-51.
Shan H, Ni Y, Xue K et al. Type 1 Retinopathy of Prematurity and Its Laser Treatment of Large Preterm Infants in East China. PLoS ONE, 2015;10(12):e0144313.
Zijing L, Yichi Z, Yunru L et al. Comparison of efficacy between anti-vascular endothelial growth factor (VEGF) and laser treatment in Type-1 and threshold retinopathy of prematurity (ROP). BMC Ophthalmol, 2018; 18: 19.
Email this article (Login required) 
