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Foam sclerotherapy—a review

Angel Angelov, Martina Sapundzhieva-Nikolova, Georgi Angelov, Veselin Petrov

Abstract

Introduction: Primary varicose veins mainly cover the great saphenous vein (VSM) and the small saphenous vein (VSP) basins of the lower extremities. The treatment procedure for their removal, the so-called radical varicophlebectomy, can be performed by the standard open technique—crossectomy and stripping, by minimally invasive methods—radiofrequency and laser ablation, and by intralumenal application of a sclerosing agent.

Literary Review: This publication details the possibility of obtaining a highly viscous foam, the route of administration into a varicose vein, and the subsequent additional treatment procedures. The rules for treatment with sclerosing of high-viscosity foam, which have been established at the end of 2006 by more than 30 world phlebologists, are described in detail.

Discussion: Foam sclerotherapy of various forms of varicose veins is a uniquely good and inexpensive method for radical treatment of superficial varicose veins. Even if the recurrence rate after penosclerotherapy is slightly higher than in other minimally invasive treatments, foam treatment is an affordable, inexpensive, and highly effective method, as long as it is performed according to accepted rules.

Conclusion: This material summarizes the positive results of foam sclerosing treatment performed according to clearly established rules.


Keywords

foam sclerotherapy, foaming, chemical ablation

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References

А. Ангелов, Ендолуменна лазерна аблация на стволови разширени вени, монография, Медицински университет – Варна, 2019, 65-70, 84-88, 121-125.

Alos J, Carreno P, Lopes JA et al. Efficacy and safety of sclerotherapy using Polidocanol foam: a controlled clinical trial. Eur J Vasc Endovasc Surg 2006; 31: 101-107.

Bidewai A, Beresfort T, Dialynas M et al. Balloon control of the of the saphenofemoral junction during foam sclerotherapy: proposed innovation. J Vasc Surg 2007; 46: 145-147.

Blaise S, Bosson JL, Diamand JM: Ultrasound guided sclerotherapy of the great saphenous vein with 1 % vs 3 % Polidocanol foam: a multicenter double-blind randomized trial with 3 years follows up. Eur J Vasc Endovasc Surg 2010; 39.

Breu FX, Guggenbichler S, Wollmann JC, 2nd European Consensus Meeting on Foam Sclerotherapy, 28-30 April 2006, Tegernsee, Germany. Vasa 2008, 37 (Suppl 71): 1-32.

Brodersen JP. Catheter-assisted vein sclerotherapy: A new approach for sclerotherapy of the greater saphenous vein with a double-lumen balloon catheter. Dermatol Surg 2007; 33: 469-475.

Chapman-Smith P, Browne A: Prospective five-year study of ultrasound guided foam sclerotherapy in the treatment of great saphenous vein reflux. Phlebology 2009; 24: 183-188.

De Waard MM, Der Kinderen DJ. Duplex ultrasonography-guided foam sclerotherapy of incompetent perforator veins in a patient with bilateral venous leg ulcers. Dermatol Surg 2005; 31: 580-583.

Goldman PM, Beadoing D, Marley W at al. Compression in the treatment of leg telangiectasia: A preliminary report. J Dermatol Surg Oncol 1990; 16: 322-325.

Hahn M, Schutz T, Jünger M. Sonographically guided, transcatheter foam sclerotherapy of the great saphenous vein. Medical and economic aspects. Phlebology 2007; 36: 309-312.

Hamel-Desnos C, Desnos P, Wollmann JC et al. Evaluation of the efficacy of Polidocanol in the form of foam compared with liquid form in sclerotherapy of the long saphenous vein: initial results. Dermatol Srg 2003; 29: 1170-1175.

Herzmann PA, Owens R. Rapid healing of chronic venous ulcers following ultrasound-guided foam sclerotherapy. Phlebology 2007; 22: 34-39.

Hübner K, Praktische Sklerotherapie, 2008, 142-160, 164-185.

Kahle B, Leng K, Efficacy of sclerotherapy in varicose veins – a prospective, blinded placebo controlled study. Dermatol Surg 2004; 30: 723-728.

Kern P, Ramelet AA, Wütschert R, Hayoz D. Compression after sclerotherapy telangiectasias and reticular leg veins. A randomized controlled study J Vasc Surg 2007; 45: 1212-1216.

Kölbel T, Hinchliffe RJ, Lindbal B: Catheter-directed foam sclerotherapy of axial saphenous reflux. Early results. Phlebology 2007; 22: 219-222.

Kressler: Fachinformation Aethoxysklerol 0,25%, 0,5 %, 1 %, 2 % und 3 %; Stand Oktober 2009, Chemische Fabrik Kreussler & Co GmbH.

Pang KH, Rate GR, Darvall KAL, Adam DJ, Bradbury AW. Healing and recurrence rates following ultrasound guided foam sclerotherapy of superficial venous reflux in patients with chronic venous ulceration. Eur J Vasc Endovasc Sutg 2010; 40: 790-795.

Ouvry P, Allaert FA, Desnos P, Hamel-Desnos C: Efficacy of polidocanol foam versus liquid sclerotherapy of the great saphenous vein: A multicenter randomized controlled trial with 2-year follow up. Eur J Vasc Surg 2008; 36: 366-370.

Rabe E, Otto J, Schliephake D, Pannier F Efficacy and safety of great saphenous vein sclerotherapy using standardized polidocanol foam (ESAF): A randomized controlled multicenter clinical trial. Eur J Endovasc Vasc Surg 2008; 35: 2238-2245.

Rabe E, Pannier F, Gerlach F, Breu FX., Guggenbichler S., Wollmann JC., Leitlinie Sklerosierungsbehandlung der Varikose, Phlebologie 2008; 37; 27-34.

Rabe E, Pannier-Fischer F, Gerlach F. et al. Guidelines for sclerotherapy of varicose veins. Dermatol Surg 2004; 30; 687-693.

Rabe E, Schliephake D, Otto J, Breu FX, Pannier F: Sclerotherapy of telangiectasis and reticular veins : a double-blind, randomized comparative clinical trial of polidocanol, solidum tetradecyl sulphate and isotonic saline (EASI study). Phlebology 2010; 25:124-131.

Rabe E, Gerlach F, Breu FX, Guggenbichler S, Stücker M, Pannier F, Leitlinie: Sklerosierungsbehandlung der Varikose, Phlebologie 2012; 4: 3-10.

Rasmussen LH et al. Randomized linical trial comparing endovenous laser ablation, radiofrequency ablation, foam sclerotherapy and surgical stripping for great saphenous varicose veins. Br J Surg 2011; 98: 1079-1087.

Stanley PRW, Bickerton DR, Campbell WB: Injection sclerotherapy for varicose veins – a comparison of materials for applying local compression. Phlebology 1991; 6:37-39.

Stücker M, Reich S, Hermes H et al. Safety and efficiency of perilesional sclerotherapy in leg ulcer with postthrombotic syndrome and/or oral anticoagulation with Phenoprocoumon. JDDG 2006; 4: 734-738.

Weiss RA, Sadick NS, Goldman MP, Weiss MA: Post-sclerotherapy compression: controlled comparative study of duration of compression and its effects on clinical outcome. Dermatol Surg 1999; 25: 105-108.

Wildenhues B. Catheter assisted foam sclerotherapy: A new minimally invasive method for the treatment of the trunk varicose of the long and short saphenous veins. Phlebology 2005; 34: 165-170.

Wollmann JC, The history of sclerosing foams, Dermatol Surg 2004; 30; 694-703.

Yamaki T, Nozaki M, Sakurai H et al. Prospective randomized efficacy of ultrasound-guided foam sclerotherapy compared with ultrasound guided liquid sclerotherapy the treatment of symptomatic venous malformations. J Vasc Surg 2008; 47: 578-584.




DOI: http://dx.doi.org/10.14748/hl.v25i1.8396

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