Background:
Saliva is the main biological oral environment in which the oral cavity processes take place. Its presence has a role in maintaining healthy oral tissues and protecting dental tissues.
Aim:
The aim is to make an up-to-date reading of the studies of Bulgarian and foreign authors and to summarize the data from scientific literature and from own researches in order to reveal the clinical potential of saliva for its full use.
Materials and Methods:
In Google scholar, Web of Science, PubMed, Scopus and ScienceDirect a search is conducted for a period of 31 years. The keywords are: "saliva", "research", "biological marker", "oral health".
Results:
Saliva has many advantages - one of the largest is the presence therein of substances that come from the gingival fluid, and the local blood flow of the salivary glands. Therefore changes in its components are proportional to those in the blood serum. It is the most affordable and non-invasive biofluid the human body. Saliva offers many advantages as a diagnostic fluid - it can easily be assembled, no special device or device is required and it contains serum components.
Conclusion:
Saliva has clinical potential for its full use in many areas of medicine. This is the future development of dental science - good synergy and cooperation between it and medicine. This will improve not only the oral but also the general health of the people.
Ботева Е, Караяшева Д, Пейчева К. Орален клирънс на хранителни продукти с високо съдържание на мазнини. Наука Диететика 2014: 3–4 : 42-47
Караяшева Д. Роля на слюнката в етиопатогенезата на зъбния кариес; София 2015
Караяшева Д, Ботева Е. Температурата като фактор в състава, качествата и количеството на слюнката и в кариесната активност. Сп. Наука Ендокринология 2014; 2: 65- 67
Караяшева Д., Маринова М., Ботева Е. Слюнка – секреция, диагностична среда, хранене и орална патология. Сп. Нови диагностични методи 2012; 4:125-137
Константинова Д, Ненова-Ногалчева А, Танчева С, Слюнката като алтернативна среда за изследване на секреторен имуноглобулин а (siga) в слюнка при пациенти в терминален стадий на хронично бъбречно заболяване на заместително лечение. Сп. Варненски медицински форум 2017, 6 (2): 54-58
Abbate J., Guynup Sh. Oral health goes modern. Journal Scientific American October 19, 2016; 315 (4)
Crossner CG1, Hase JC, Birkhed D. Oral sugar clearance in children compared with adults. Caries Res. 1991;25(3):201-6.
Greenman J et alStudy on the organoleptic intensity scale for measuring oral malodor J. Dent Res. 2004 ;83 ;81–5
Mandel ID.The diagnostic uses of saliva. J Oral Pathol Med. 1990 Mar; 19 (3): 119-25
Moreno EC, Varughese K, Hay DI: Effect of human salivary proteins on the precipitation kinetics of calcium phosphate.Calcif Tissue Int 1979; 28:7–16
Newbrun E. Preventing dental caries. Current and prospective strategies. Journal of the American Dental Association 1992; 123: 68–73
Schlesinger DH, Hay DI: Complete covalent structure of a proline-rich phosphoprotein, PRP-2, an inhibitor of calcium phosphate crystal growth from human parotid saliva.Int J Peptide Res 1986; 27:373–379
Sinor Z, Azirrawani A. Association between salivary parameters and periodontal disease. Int Med J. 2013; 20: 1–5
Van den Broek A, Feenstra L, de Baat C, A review of the current literature on management of halitosis; Oral Dis. 2008; 14, 30–39
www.gcamerica.com/storage/dps_c/GCA_Saliva-Check_BUFFER-iPad.pdf
www.gceurope.com/products/salivacheckmutans
www.ivoclarvivadent.com/en/p/
Zilm PS, Mira A, Bagley CJ, Rogers AH Effect of alkaline growth pH on the expression of cell envelope proteins in Fusobacterium nucleatum. Microbiology. 2010 Jun; 156 (Pt 6):1783-94
