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Izvestia Journal of the Union of Scientists - Varna. Medicine and Ecology Series

Gallbladder adenomyomatosis mimicking carcinoma - a clinical case

Diana Todorova Gancheva-Tomova, Radoslav Georgiev, Ivan Krasnaliev


Gallbladder adenomyomatosis is hyperplastic cholecystosis of the gallbladder. This is a relatively common and benign cause for diffuse or focal wall thickening.

We present a case of a 48-year-old woman with complaints from 3 - 4 years of epigastric pain, abdominal swelling, occurring after eating, with a temporary effect after antispasmodics or antisecretors. There was a reduction in body weight. All laboratory tests were normal. An ultrasound examination revealed a diffusely thickened, stratified gallbladder wall and parenchymal mass in the lumen. Due to clinical suspicion of acalculous cholecystitis, antibacterial treatment was performed, which did not lead to relief of symptoms. The ultrasound picture also did not change. Magnetic resonance imaging showed an image of gallbladder adenomyomatosis. Given the differential diagnostic possibility of gallbladder cancer, a planned cholecystectomy was performed, which, together with histological examination, confirmed the benign nature of the disease. After the surgery, the patient's complaints completely disappeared.

Gallbladder adenomyomatosis is a benign and degenerative condition characterized by mucosal proliferation and thickening of the muscle layer. Given the possible premalignant character, cholecystectomy remains the treatment of choice for patients with clinically manifested gallbladder adenomyomatosis.





gallbladder adenomyomatosis, gallbladder carcinoma, diagnosis

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